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Found 34 clinical trials
Point-of-care Urine Monitoring of Adherence (PUMA): Testing a Real-Time Urine Assay of Tenofovir in PrEP (PUMA)

Worldwide expansion of pre-exposure prophylaxis (PrEP) with oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) will be critical to ending the HIV epidemic. However, maintaining daily

Accepts healthy volunteers
  • 0 views
  • 15 Jun, 2022
  • 1 location
Switch to TAF+FTC+BIC in HIV-1-infected Patients Over 65 Years Old at Risk of Polymedication (BICOLDER)

. Bictegravir, co-formulated with emtricitabine (FTC) and tenofovir alafenamide (TAF) (BIKTARVY) a new generation integrase inhibitor with a high genetic barrier and had no drug interaction may be a treatment

emtricitabine
tenofovir
ritonavir
cobicistat
integrase inhibitors
  • 0 views
  • 29 Jun, 2022
  • 6 locations
HIV Pre-exposure Prophylaxis Implementation Study in South Korea

provided open-label tenofovir/emtricitabine (TDF/FTC) for PrEP in South Korea. Secondary objectives are 1) to evaluate HIV incidence among study participants, 2) to evaluate risk behavior and risk

emtricitabine
tenofovir
HIV Vaccine
pre-exposure prophylaxis (prep)
immune globulin
  • 0 views
  • 26 Jan, 2021
Doravirine for Persons With Excessive Weight Gain on Integrase Inhibitors and Tenofovir Alafenamide

/emtricitabine) (TAF/3TC (lamivudine)) regimen could either slow their rate of weight gain or lose weight within about 1 year if they switch to a regimen containing doravirine (DOR; a newer, non-nucleoside

hysterectomy
emtricitabine
tenofovir
dolutegravir
HIV Vaccine
  • 48 views
  • 15 Mar, 2022
  • 21 locations
Rapid Start vs. Standard Start Antiretroviral Therapy (ART) in HIV

This study plans to learn about whether starting HIV treatment very soon after diagnosis is more beneficial than waiting until entering routine clinical care after diagnosis.

  • 0 views
  • 28 Jan, 2021
  • 3 locations
Harm Reduction Program For Informal PrEP Users In A Community-based Setting (seguiPrEP) (seguiPrEP)

controlled and randomized clinical trials, as well as implementation projects have shown that the use of tenofovir disoproxil (TDF) and emtricitabine (FTC) is both safe and effective in the prevention of HIV

enzyme-linked immunosorbent assay
antiretroviral agents
elisa
tenofovir
Accepts healthy volunteers
  • 4 views
  • 12 Feb, 2022
  • 1 location
Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant Women. (APR)

The purpose of the Antiretroviral Pregnancy Registry (Registry) is to detect any major teratogenic effect involving any of the Registry drugs when administered to pregnant women. Registration is voluntary and confidential with information obtained from the health care provider. A Registry-assigned identifier allows for follow-up capability. Information on subjects is …

antiretroviral agents
HIV Vaccine
antiretrovirals
prenatal
antiretroviral
  • 70 views
  • 04 May, 2022
  • 1 location
Pharmacokinetics of Antiretroviral Agents in HIV-infected Pregnant Women. (PANNA)

Due to the potential for pregnancy-induced changes in the pharmacokinetics of medication, one cannot assume that the currently licensed doses of the medication to be tested under this protocol lead to adequate exposure in an HIV-infected pregnant woman. For the agents under study no or limited pharmacokinetic data during pregnancy …

antiretroviral agents
HIV Vaccine
antibody test
immune globulin
hiv antibody
  • 156 views
  • 23 Jan, 2022
  • 16 locations
Same-Day Antiretroviral Therapy Initiation

Data from a total of 2,500 walk-in or referred individuals who have been confirmed (diagnosed) HIV positive and accessing care and treatment services at the hospitals targeted by this study will be examined. The starting period for this project is estimated to be the last quarter (Q4) of fiscal year …

antiretroviral therapy
antiretroviral agents
HIV Vaccine
antiretroviral
  • 61 views
  • 13 Feb, 2022
  • 11 locations
Role of Exogenous and Endogenous Sex Hormones on Tenofovir and Emtricitabine Disposition in Female Genital Tract

Cervical biopsies will be collected from women aged 18 and over whom are virally suppressed and taking tenofovir as part of their antiretroviral therapy regimen. Blood plasma, peripheral blood mononuclear cells (PBMC), and cervicovaginal swabs will also be collected. Drug concentrations, hormone concentrations, inflammatory cytokines, and vaginal microbiome will be …

sex hormones
emtricitabine
antiretroviral agents
tenofovir
antiretrovirals
  • 36 views
  • 23 Apr, 2022
  • 1 location