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Found 48 clinical trials
Featured trial
A phase III randomized, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with reduced Ejection Fraction (HFrEF).

A phase III randomized, double-blind trial to evaluate efficacy and safety of once daily empagliflozin 10 mg compared to placebo, in patients with chronic Heart Failure with reduced Ejection Fraction

  • 378 views
  • 25 Mar, 2021
  • 1 location
Featured trial
This clinical study will measure the effectiveness of a new adjunctive treatment for people with type 1 diabetes.

This clinical study will measure the effectiveness of a new adjunctive treatment for people with type 1 diabetes.

  • 276 views
  • 23 Nov, 2020
  • 1 location
Randomised, Double-blind, Placebo-controlled and Parallel Dose Group Trial to Investigate Efficacy and Safety of Multiple Doses of Oral BI 690517 Over 14 Weeks, Alone and in Combination With Empagliflozin, in Patients With Diabetic and Non-diabetic Chronic Kidney Disease

called BI 690517 improves kidney function in people with chronic kidney disease when taken alone or in combination with a medicine called empagliflozin. In the first part of the study

  • 27 views
  • 27 Oct, 2022
  • 210 locations
Efficacy and Safety of Metformin Versus Empagliflozin on Chronic Kidney Disease Progression

This randomized controlled trial aims at evaluating the efficacy and safety of the antidiabetics metformin versus empagliflozin on chronic kidney disease (CKD) progression in patients with CKD

  • 0 views
  • 27 May, 2022
  • 2 locations
In-hospital Initiation of Empagliflozin for the Treatment of New-onset Acute Heart Failure Regardless of Ejection Fraction: A Pilot Study (EMPA)

cotransporter-2 (SGLT2) inhibitor is considered one of the four foundational therapies (ACE-I or ARNI, beta-blockers, MRA, and SGLT2 inhibitors) for HFrEF. In particular, empagliflozin has been shown in

  • 0 views
  • 21 Oct, 2022
  • 1 location
SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial

This study will test whether pharmacologic agents that may improve mitochondrial function and energy fuel metabolism [Empagliflozin (Empa)], with and without additional supplements that increase

  • 0 views
  • 07 Jun, 2022
  • 1 location
Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs

of a 4-month polychemotherapy (metformin+pioglitazone+sitagliptin+empagliflozin) regimen vs standard care in patients with newly diagnosed T2DM by an open label, pragmatic RCT. Mechanisms of action

  • 2 views
  • 23 Aug, 2021
  • 1 location
Heart Failure Patients With Left Ventricular Assist Devices Being Treated With Sodium-Glucose Co-Transporter 2 Inhibitors

The main purpose of this study is to observe outcomes of sodium-glucose co-transporter 2 inhibitors (SGLT2i) in heart failure (HF) patients with left ventricular assist devices (LVAD).

  • 0 views
  • 23 Oct, 2022
  • 1 location
EMPACT-MI: A Streamlined, Multicentre, Randomised, Parallel Group, Double-blind Placebo-controlled Superiority Trial to Evaluate the Effect of EMPAgliflozin on Hospitalisation for Heart Failure and Mortality in Patients With aCuTe Myocardial Infarction

This is a study in adults who had a heart attack (myocardial infarction). The purpose of this study is to find out whether a medicine called empagliflozin helps to lower the chances of having to

acute myocardial infarction
atherosclerosis
stemi
infarct
st elevation myocardial infarction
  • 204 views
  • 24 Oct, 2022
  • 437 locations
Randomised Evaluation of COVID-19 Therapy (RECOVERY)

), Convalescent plasma, Casirivimab+Imdevimab, Tocilizumab, Aspirin, Baricitinib, Infliximab, Empagliflozin, Sotrovimab, Molnupiravir, Paxlovid or Anakinra (children only) prevents death in patients with COVID-19

pneumonia
ritonavir
influenza
covid-19
hydroxychloroquine
  • 0 views
  • 19 Apr, 2022
  • 6 locations