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Found 26 clinical trials
Featured trial
Eltrombopag for People With Fanconi Anemia

Fanconi anemia is a genetic disease. Some people with it have reduced blood cell counts. This means their bone marrow no longer works properly. These people may need blood transfusions for anemia (low red blood cells) or low platelet counts or bleeding. Researchers want to see if a new drug …

anemia studies
fanconi's anemia
fanconi's syndrome
anemia
  • 143 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

attacking the bone marrow. However, this treatment does not work in all people. Some people still have poor blood cell counts even after treatment. Eltrombopag is a drug designed to mimic a protein

myelodysplastic syndrome (mds)
anemia studies
anemia
myelodysplastic syndromes
aplastic anemia
  • 172 views
  • 22 Dec, 2020
  • 1 location
Featured trial
A Randomized Trial of Sirolimus (Rapamune) for Relapse Prevention in Patients with Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

Background: People with severe aplastic anemia (SAA) do not make enough red and white blood cells, and/or platelets. Their body's immune system stops the bone marrow from making these cells. The treatment cyclosporine leads to better blood counts. But when this treatment is stopped, the disease may return in 1 …

myelodysplastic syndrome (mds)
anemia studies
anemia
myelodysplastic syndromes
aplastic anemia
  • 75 views
  • 22 Dec, 2020
  • 1 location
Eltrombopag Plus Diacerein vs Eltrombopag in Adult ITP

dose. Diacerein is a slow-acting medicine of the class anthraquinone used to treat joint diseases such as osteoarthritis. We speculate that the addition of diacerein to eltrombopag may offer sensitizer

eltrombopag
platelet count
  • 1 views
  • 19 Jun, 2021
  • 1 location
Immunomodulation With Eltrombopag in ITP (iROM2)

The study aims to investigate immunomodulatory effects of eltrombopag combined with dexamethasone in young and midlife adult patients with newly diagnosed primary Immune thrombocytopenia (ITP

  • 0 views
  • 14 Jul, 2022
  • 6 locations
Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

transfusions regularly which are time consuming and can have significant side effects. The drug eltrombopag can increase red blood cells. Researchers want to see if it can help people with DBA and, if so, for

cell counts
  • 2 views
  • 27 Jul, 2022
  • 1 location
Eltrombopag+hATG+CsA vs. hATG+CsA in Children With Severe AA

adding eltrombopag to standard immunosuppressive therapy

  • 78 views
  • 26 Feb, 2022
  • 1 location
Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)

SSA is a combination of 3 drugs (Cyclosporine [CsA], Eltrombopag [EPAG], and horse anti-thymocyte globulin [h-ATG]). Researchers want to see if starting people at a lower dose of CsA with EPAG before

eltrombopag
platelet count
antithymocyte globulin
aplastic anemia
reticulocyte count
  • 12 views
  • 26 Jul, 2022
  • 1 location
Efficacy and Safety of Romiplostim Versus Eltrombopag in the Treatment of Thrombocytopenia in Patients With Wiskott-Aldrich Syndrome

This is a prospective, open-label, randomized, two-arm clinical trial conducted to evaluate the safety and efficacy of romiplostim in comparison with eltrombopag in the treatment of

  • 6 views
  • 04 Mar, 2022
  • 1 location
Identification and Validation of Biomarkers for Breast Cancer Resistance Protein (BCRP) (BCRPmarker)

This is an open-label, non-randomized, fixed-sequence study. Subjects will undergo a rosuvastatin phase and eltrombopag and rosuvastatin phase to identify biomarkers for Breast Cancer Resistance

Accepts healthy volunteers
  • 0 views
  • 16 May, 2022
  • 1 location