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Found 44 clinical trials
Psychotherapeutic Augmentation of Brain Stimulation Effects

This study aims to investigate effectiveness and feasability of a 15-week group psychotherapeutic intervention as continuation treatment after electroconvulsive therapy in severely depressed

electroconvulsive therapy
depressed
brain stimulation
depressed mood
psychotropic drugs
  • 5 views
  • 15 Feb, 2021
  • 2 locations
A Pilot Study of Creatine Monohydrate as an Augmenting Agent for ECT in Persons With Major Depressive Disorder

We propose to determine if augmentation of electroconvulsive therapy (ECT) utilized for the treatment of major depressive disorder (MDD) with daily oral creatine will lead to an accelerated

major depressive disorder
electroconvulsive therapy
creatine monohydrate
depression
  • 0 views
  • 25 Jan, 2021
  • 1 location
NESBID: Neuro-Stimulation of the Brain in Depression

of choice has historically consisted of electroconvulsive therapy (ECT), this is not always feasible or practical, and carries a risk of side-effects that may be unacceptable to certain patients.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Comparison of Thiopental and Propofol as Anaesteticum During ECT

Electroconvulsive therapy is the most effective treatment in severe depression and the effect is related to the generalized seizure induced by the treatment. General anesthesia is used

major depressive disorder
electroconvulsive therapy
severe depression
  • 9 views
  • 07 Nov, 2020
  • 1 location
Title: Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)

Background Electroconvulsive therapy (ECT) is used to treat people with severe depression. During ECT, the brain is given electric pulses that cause a seizure

electroconvulsive therapy
severe depression
depressed mood
anesthesia
depressive disorder
  • 6 views
  • 05 May, 2021
  • 1 location
Deep Brain Stimulation (DBS) for Depression Using Directional Current Steering and Individualized Network Targeting

The goal of the study is to address the unmet need of TRD patients by identifying brain networks critical for treating depression and to use next generation precision DBS with steering capability to engage these targeted networks. The study's goal will be achieved through 3 specific aims: Demonstrate device capability …

ketamine
brain stimulation
antidepressants
lithium
psychotherapy
  • 0 views
  • 04 May, 2021
  • 2 locations
Triple Chronotherapy in Adolescents

Study Purpose This study is a randomized controlled trial examining the effectiveness of TCT in the acute treatment of depression and suicidality in adolescents compared to usual treatment care, which includes individual and group therapy, and medication adjustments. All potential participants will be identified at admission to the Psychiatric Youth …

insomnia
severe depression
depressed mood
psychotherapy
depressive symptoms
  • 12 views
  • 25 Jan, 2021
  • 1 location
Neurobiological Underpinnings of Placebo Response in Depression

In summary, the proposed research is novel with respect to design, technology, and its multi-level integration probing psychological and neurobiological constructs assumed to be crucially implicated in placebo response and has significant clinical and research implications for the future. Specifically, the future implications include: 1) identification of biomarkers and biosignatures …

bupropion
anxiety
antidepressants
  • 19 views
  • 18 Apr, 2021
  • 1 location
The Effecay and Prediction of Deep Brain Stimulation for Treatment-resistant Depression

Several open-label trials have shown the therapeutic promise of deep brain stimulation (DBS) targeted to striatal and surrounding capsular areas in treatment-resistant depression (TRD). However, the results of placebo-controlled trials have been mixed, with one showing a large difference between active and sham DBS and another finding no difference. Main …

brain stimulation
depression
major depressive disorder
lithium
selective serotonin reuptake inhibitors
  • 0 views
  • 02 May, 2021
  • 1 location
Transcranial Direct Current Stimulation (tDCS) Therapy in Major Depression

Noninvasive transcranial direct current stimulation (tDCS) is a low-intensity neuromodulation technique of minimal risk that has been used as an experimental procedure for reducing depressive symptoms and symptoms of other brain disorders. Though tDCS applied to prefrontal brain areas is shown to reduce symptoms in some people with major depressive …

selective serotonin reuptake inhibitors
antidepressants
major depressive disorder
norepinephrine
depressive symptoms
  • 0 views
  • 05 May, 2021
  • 1 location