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Found 367 clinical trials
Influence of Systemic Parameters in Diabetic Macular Edema - LIPSIA Study

This study aims to evaluate the influence and prognostic value of systemic factors (such as the cardiovascular and metabolic status) on the treatment response to anti-VEGF therapy in macular edema due to diabetes or retinal vein occlusion.

retinal vein occlusion
anti-vegf therapy
diabetic macular edema
  • 22 Jan, 2021
Prognostic and Clinical Impact of Cardiovascular Involvement in Patients With COVID-19

COVID-19 infection has been associated with numerous cardiac manifestations. Indeed, SARS-CoV-2 may impact on cardiovascular system through a direct myocardial infection or a secondary cardiac involvement due to hypoxia or metabolic supply-demand imbalance or prothrombotic inflammatory state. As a consequence of and besides acute myocardial damages, COVID-19 could also determine …

  • 26 Jan, 2021
  • 5 locations
Evaluation of Reliability and Validity of Reflectance Pulse Oximeter in Screening Children With Obstructive Sleep Apnea

Polysomnography (PSG) has some disadvantages, such as time-consuming, effort-consuming, long appointment time and high cost. During PSG examination, multiple sensors need to be placed in the patient's head, face, neck, chest and limbs, and sensors are needed to monitor data throughout the night. It is difficult for young children to …

  • 21 Aug, 2021
  • 1 location
Predictors of Atrial Fibrillation in Patients Undergoing Implantable Loop Recorder Implant

Implantable Loop Recorders (ILR) are small devices the size of a memory stick, which are implanted to investigate stroke, palpitations and fainting episodes. They monitor the heart constantly and detect abnormalities such as slow or fast heart beats and an irregular heartbeat called Atrial Fibrillation (AF). Stroke is a life …

  • 28 Jan, 2021
  • 1 location
Utility of Thenar Near Infrared Spectroscopy (NIRS) in Pediatric Patients With Heart Failure

This is a single-center, non-randomized study.The study staff will use the InSpectraTM tissue oxygen saturation (StO2) monitor manufactured by Hutchinson Technology to measure baseline StO2 levels after applying the noninvasive probe to the thenar eminence. After a stable reading is obtained, a blood pressure cuff will be inflated 40 mmHg …

heart disease
heart failure
  • 07 Mar, 2021
  • 1 location
Pharmacokinetics and Pharmacogenomics of Ribociclib in Race-based Cohorts

The aim is to determine the pharmacological and biochemical association between ribociclib exposure and CYP3A variants in African American/Blacks and Non-Hispanic White patients. The investigators hypothesize that patients treated with ribociclib who are CYP3A5 poor metabolizers may be exposed to higher levels of ribociclib than CYP3A5 intermediate or normal metabolizers. …

endocrine therapy
hormone therapy
  • 01 Aug, 2021
  • 3 locations
Emotional Proactive Brain Study in Adults With Autism Spectrum Condition

This project aims: to study behavioral and cerebral activity specificity (latency and amplitude of evoked potentials, time frequency maps and cerebral connectivity) in predictive process (top-down regulation) during visual recognition of static and dynamic stimuli in adults participants with autism spectrum conditions compared to typically developed participants. to study the …

  • 08 Apr, 2021
  • 1 location
Cardiac Manifestation and Inherited Metabolic Diseases

The aim of this study is to report and describe cardiac manifestations associated with IMD in a cohort of patients followed in a reference center for rare diseases (Lausanne University Hospital, CHUV) from 2017-2020.

  • 22 Aug, 2021
  • 1 location
Romanian Kidney Transplant Cardiovascular Risk Registry

Kidney transplantation (KT) represents the best treatment for patients with end-stage kidney disease, being associated with improved outcomes and reduced mortality. Although the survival benefit with KT is mostly attributable to reduction in cardiovascular (CV) disease, KT recipients continue to remain at higher risk for CV-related morbidity and mortality when …

kidney disease
chronic renal failure
  • 24 Jan, 2021
  • 1 location
Vagus Nerve Response in Gastroparesis Patients

This study aims to characterize how vagus nerve compound action potentials (CNAPs) conduct along the vagus nerve in gastroparetic patients receiving GES therapy using a flexible, non-invasive multielectrode array (MEA).

  • 23 Jan, 2021
  • 1 location