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Found 54 clinical trials
Oncodrivers in Malignant Pleural Effusions Associated With Non-small Cell Lung Cancer: A Prospective Study.

Oncological treatment of patients with disseminated non-small cell lung cancer (NSCLC) is depending on the status of programmed death-ligand 1 (PD-L1), anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR), so called oncodrivers. These can be measured in pleural fluid, but the prevalence is uncertain. In a prospective study, …

epidermal growth factor receptor
EGFR
pleural effusion
diagnostic procedure
cancer
  • 0 views
  • 26 May, 2022
Tunneled Pleural Catheters for Refractory Effusions Attributed to Congestive Heart Failure (TREAT-CHF) Trial (TREAT-CHF)

Congestive heart disease (CHF) can frequently cause transudative pleural effusions, some of which do not completely resolve with diuretics alone. These effusions can cause significant morbidity

ejection fraction
heart disease
diastolic dysfunction
angiotensin converting enzyme
diuretics
  • 10 views
  • 05 Jun, 2022
  • 1 location
Diagnosis and Classification of Pleural Diseases Using Ultrasound Channel Data

them are included Pneumothorax (Air the chest cavity), Pleural effusions, and tumor formation. Ultrasound imaging of the Pleura to detect and assess pleural diseases has been proven as an

cavity
pneumothorax
diagnostic procedure
  • 0 views
  • 28 Sep, 2021
  • 1 location
Intrapleural Fibrinolytic Therapy to Enhance Chemical Pleurodesis Enhance Chemical Pleurodesis

Prospective Randomized Double-Blind Controlled Trial of Intrapleural Fibrinolytic Therapy to Enhance Chemical Pleurodesis versus Standard of care Talc therapy in patients with recurrent pleural effusion.

  • 0 views
  • 12 Sep, 2021
  • 1 location
Pigtail Catheter: a Less Invasive Option for Pleural Drainage of Recurrent Hepatic Hydrothorax

The effectiveness of pigtail catheter as a less invasive option for pleural drainage in patients with resistant hepatic hydrothorax.

drainage
pleural fluid analysis
serum protein
  • 26 views
  • 21 Jan, 2021
  • 1 location
Thoracic Ultrasound in the Treatment of Pleural Effusion

The main objective of the study is to assess the cost-effectiveness ratio of two management strategies of pleurisy in adults : a strategy by systematic thoracic ultrasound versus a strategy without thoracic ultrasound.

thoracic ultrasound
  • 44 views
  • 26 Jan, 2021
  • 1 location
Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System (NEWTON)

Malignant pleural effusion remains a debilitating complication of end stage cancer, which can be greatly improved by the introduction of the indwelling tunneled pleural catheter (IPC). However, there is no standard of care regarding drainage and limited data on the utility of different drainage techniques. In addition, many patients develop …

end stage cancer
cavity
discomfort
dyspnea
malignant pleural effusion
  • 2 views
  • 26 Feb, 2022
  • 5 locations
GRAvity- Versus Wall Suction-drIven Large Volume Thoracentesis: a rAndomized Controlled Study (GRAWITAS Study)

The primary objective of this study is to compare gravity-driven versus wall suction-driven large volume therapeutic thoracentesis on the development of chest discomfort during the procedure. This study is a multicenter, single-blinded, randomized controlled trial designed to compare chest discomfort between gravity-driven and wall suction-driven therapeutic thoracentesis. Patients will be …

  • 0 views
  • 29 Nov, 2021
  • 1 location
Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural Effusion

The purpose of this study is to compare the experiences of subjects who drain malignant (cancerous) pleural effusions (fluid) from around their lung(s) in a more frequent manner using a talc

dyspnea
pleural fluid analysis
malignant pleural effusion
drainage
thoracentesis
  • 0 views
  • 28 Jul, 2021
  • 1 location
Urine Bag Usage Versus Chest Drain Clamping After Lung Resection Surgeries

Investigators will compare two different approaches of postoperative drainage after the standard water-seal drain has been used efficiently; one is by using urine bag and check it get blown by the leaked air, two is by using clamping of the water seal drain. Investigators will compare them depending on several …

drainage
  • 0 views
  • 22 Mar, 2022