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Found 779 clinical trials
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A Prospective, Randomized, Double-masked, Active Comparator-controlled, Multi-center, Two-arm, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Visual Impairment Due to Treatment-naïve Macular Edema Secondary to Retinal Vein Occlusion (RVO)

This Phase 3 study will evaluate the efficacy, durability, and safety of KSI-301 compared to aflibercept, in participants with macular edema due to treatment-naïve branch (BRVO) or central retinal

spectral domain optical coherence tomography
retinal vein occlusion
macular edema
aflibercept
  • 0 views
  • 24 Jun, 2021
  • 1 location
featured
  • 0 views
  • 24 Jun, 2021
  • 1 location
featured
ASTRAL

BIIB093 is an investigational product under development for the treatment and prevention of severe cerebral edema in patients with large hemispheric infarction (LHI) and for the treatment of brain

  • 30 views
  • 11 Jun, 2020
  • 1 location
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Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction

The primary objective is to determine if BIIB093 improves functional outcome at Day 90 as measured by the modified Rankin Scale (mRS) when compared with placebo in participants with Large Hemispheric Infarction (LHI). The secondary objectives are to determine if BIIB093 improves overall survival at Day 90 when compared with …

  • 12 views
  • 12 Aug, 2020
  • 1 location
featured
Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction

To determine if BIIBO93 improves functional outcome at Day 90 as measured by modified Rankin Scale (mRS) when compared with placebo in subjects with Large Hemispheric infarction (LHI)  

  • 18 views
  • 23 Nov, 2020
  • 1 location
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Inflammatory Characterization of Known or Possible Cardiovascular Diseases

. Researchers want to learn if there is a relationship between these diseases and inflammation (redness, swelling, and pain). Inflammation affects the entire body. Researchers will study this relationship in

fats
heart disease
diabetes
  • 46 views
  • 23 Nov, 2020
  • 1 location
featured
Long-term effects of semaglutide on diabetic retinopathy in subjects with type 2 diabetes

We are seeking participants for a new clinical research study to evaluate the long term treatment effects of an investigational medication on diabetic retinopathy progression in adults with type 2 diabetes.  

type 2 diabetes
hemoglobin a1c
type 2 diabetes mellitus
diabetes type 2
diabetes
  • 72 views
  • 14 Jan, 2021
  • 1 location
featured
A Phase 3, Randomized, Masked, Controlled Clinical Trial to Study the Safety and Efficacy of Triamcinolone Acetonide Injectable Suspension (CLS-TA) for the Treatment of Subjects with Macular Edema associated with Non-Infectious Uveitis

A Phase 3, Randomized, Masked, Controlled Clinical Trial to Study the Safety and Efficacy of Triamcinolone Acetonide Injectable Suspension (CLS-TA) for the Treatment of Subjects with Macular Edema

  • 192 views
  • 08 Nov, 2020
  • 1 location
featured
Patients with Heart Failure and currently on a loop diuretic

shortness of breath (dyspnoea), lack of energy (fatigue), build-up of fluid (oedema), chronic coughing/wheezing and confusion.   In recognition of the time and effort involved in

furosemide
heart failure
fatigue
  • 88 views
  • 23 Nov, 2020
  • 1 location
featured
HAE - Patients diagnosed with Acute Hereditary Angioedema

HAE - Patients diagnosed with Acute Hereditary Angioedema

  • 598 views
  • 08 Nov, 2020
  • 1 location