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Found 112 clinical trials
A Phase III Clinical Trial Evaluating De-Escalation of Breast Radiation for Conservative Treatment of Stage I, Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

This Phase III Trial evaluates whether breast conservation surgery and endocrine therapy results in a non-inferior rate of invasive or non-invasive ipsilateral breast tumor recurrence (IBTR) compared to breast conservation with breast radiation and endocrine therapy.

  • 0 views
  • 21 Oct, 2022
  • 424 locations
A Study for the Adjuvant Treatment of Breast Cancer

Studies on postoperative adjuvant albumin paclitaxel in domestic breast cancer patients are less reported, especially in large samples, and more studies focus more on the safety and tolerability of albumin paclitaxel use. Head-to-head studies of white violet and docetaxel are not supported by data at this time, but some studies …

estrogen receptor
her2/neu-positive breast cancer
progesterone
carboplatin
metastasis
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Study for the Neoadjuvant Treatment of Breast Cancer

Due to the unique advantages of albumin-bound paclitaxel, several studies in China and abroad have tried to use albumin-bound paclitaxel for neoadjuvant treatment of breast cancer up to now. However, comparative studies between paclitaxel and docetaxel are still rare, In this study, a prospective, randomized, open-label, multi-center clinical study was …

estrogen receptor
her2/neu-positive breast cancer
progesterone
carboplatin
metastasis
  • 0 views
  • 04 Oct, 2022
  • 1 location
HYPofractionated Adjuvant RadioTherapy in 1 Versus 2 Weeks in High-risk Patients With Breast Cancer (HYPART).

We at PGIMER have been practicing hypofractionated radiotherapy in breast cancer patients for the last 4 decades. Our standard doses have been 35Gy/15/3wks to the chest wall after mastectomy and 40Gy/16/3wks after breast conserving surgery (BCS).It is also a routine practice in the UK and in a few centers in …

mastectomy
trastuzumab
hormone therapy
invasive carcinoma
carcinoma
  • 0 views
  • 01 Jul, 2021
  • 1 location
SABR-CaRe in Early Stage Breast Cancer

This phase II trial studies the effect of calorie reduction while undergoing stereotactic ablative radiation therapy in treating patients with breast cancer. Stereotactic ablative radiation therapy (sABR) is a highly focused radiation treatment that gives an intense dose of radiation concentrated on a tumor, while limiting the dose to the …

cancer
breast cancer
invasive breast cancer
sentinel lymph node biopsy
breast cancer staging
  • 0 views
  • 06 May, 2022
  • 1 location
CIPN in Early Stage Breast Cancer Patients

stage breast cancer patients, who are scheduled to receive taxanes, from medical oncology outpatient clinics. The investigators will ask consenting participants to make 4 or 5 separate visits to the

chemotherapy drugs
breast cancer staging
docetaxel
paclitaxel
  • 0 views
  • 04 Oct, 2022
  • 1 location
SABER Study for Selected Early Stage Breast Cancer (SABER)

The purpose of this study is to find the most effective dose of radiation therapy to give to breast tumors in a shorter period of time, prior to standard partial mastectomy/axillary surgery.

progesterone
mastectomy
lumpectomy
breast cancer stage
HER2
  • 0 views
  • 21 Mar, 2022
  • 1 location
GammaPod Dose Escalation Radiation for Early Stage Breast Cancer

radiation to treat early stage breast cancer. The pre-operative radiation is delivered using the FDA approved, GammaPod machine. The study will also determine the cosmesis of pre-operative radiation at

mastectomy
lumpectomy
carcinoma
breast cancer staging
ductal carcinoma
  • 6 views
  • 20 Nov, 2021
  • 4 locations
Single Fraction Preoperative Radiotherapy for Early Stage Breast Cancer

This is a phase I/II, single-arm and open-label single-centre clinical trial with the aim to test the feasibility, safety and the efficacy, in terms of complete pathological response, of preoperative ablative radiotherapy in single fraction for selected breast cancer patients.

breast cancer staging
breast-conserving surgery
  • 0 views
  • 02 Sep, 2021
  • 1 location
Preoperative Single-Fraction Radiotherapy in Early Stage Breast Cancer

This protocol seeks to build on the favorable results of the investigators' phase I trial (Pro00015617) by extending the findings to a larger cohort of subjects.In this study, the investigators hypothesize that 21Gy (Gray) as a single fraction can be delivered preoperatively to a larger group of subjects (n100). The …

estrogen receptor
invasive carcinoma
carcinoma
erbb2
breast cancer staging
  • 0 views
  • 18 Mar, 2022
  • 1 location