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Found 423 clinical trials
Smart Prostate Specific Antigen (PSA) Screening Study

This intervention includes the introduction of the Prostate Cancer Working Group (PCWG )Smart PSA Screening Guidelines and implementation of patient navigation/ care coordination for men with elevated PSA (>4.0 ng/mL). The guidelines include: What age to start? How often to repeat screening? What age to stop? What PSA threshold should …

  • 12 Mar, 2021
  • 1 location
The Efficacy of Automated Feedback After Internet-based Depression Screening

The DISCOVER randomized controlled trial is designed to evaluate the effect of automated feedback after internet-based depression screening in individuals with undetected depression. A total of 1076 individuals reporting elevated levels of depression (PHQ-9 score 10 points) will be randomized into three groups to either receive a) no feedback (control …

  • 10 Apr, 2021
  • 1 location
Heart Failure Events Reduction With Remote Monitoring and eHealth Support Investigator Initiated Trial

The primary objective of the study is to evaluate the efficacy of a telemedicine-based follow-up strategy compared with usual care in the management of patients with chronic heart failure (HF) at high risk of clinical events.

heart failure
ejection fraction
chronic heart failure
  • 25 Jan, 2021
  • 1 location
Screening for Occult Malignancy in Patients With Unprovoked Venous Thromboembolism

Venous thromboembolism (VTE) can be the earliest sign of cancer. Identifying occult cancers at the time of VTE diagnosis may lead to significant improvement of patients' care. This is also an upmost issue for patients who want to know if an underlying cancer might have triggered the VTE. An individual …

  • 26 Jan, 2021
  • 20 locations
A Study of Guselkumab in Participants With Active Lupus Nephritis

The purpose of this study is to evaluate the efficacy of guselkumab in participants with active lupus nephritis (LN).

angiotensin receptor blockers
antinuclear antibody
  • 25 Mar, 2021
  • 63 locations
Prevention of Obesity-related Cancers: Setting up of a Multi-Cancer Education and Prevention Program in Hong Kong

Obesity could increase the risk of many chronic diseases, including hypertension, cardiovascular diseases, high lipid level, diabetes, stroke, endometrial cancer and certain types of cancer which could benefit by secondary prevention through screening programs. The World Cancer Research Fund of the American Institute for Cancer Research has reviewed all the …

cancer screening
weight control
prostate specific antigen
  • 26 Jan, 2021
  • 1 location
Lavage of the Uterine Cavity for the Diagnosis of Serous Tubal Intraepithelial Carcinoma

The current study aims at answering the scientific question, whether exfoliated cells from STICs get transported into the uterine cavity via the fallopian tube, and whether it is possible to detect those cells in the lavage fluid from the uterine cavity and proximal fallopian tubes. To address this question, the …

fallopian tube
serous cystadenocarcinoma
  • 10 Apr, 2021
  • 17 locations
The Box 2.0: Using Smart Technology for Early Diagnosis of Complications After Cardiovascular Surgery

The objective of this study is to determine the effect on quality of care when introducing smart technology in patients who underwent cardiovascular surgery. Patients who consent to take part in the study, receive a box containing two smartphone compatible ECG monitors, an oxygen saturation monitor, a weight scale, a …

  • 27 Jan, 2021
  • 1 location
Cost-utility Analysis of the Follow-up of Exclusive Telemedicine Pacemakers Compared to Conventional Pacemakers

TELEPACE is an economic evaluation that aims to determine the probability at which Home Monitoring without physical examinations, could be cost effective, compared to the conventional treatment by face to face consultations. Patient will be randomized in a control group followed according to the current guidelines and and active group …

  • 23 Jan, 2021
  • 1 location
Development of a Horizontal Data Integration Classifier for Noninvasive Early Diagnosis of Breast Cancer

This is a translational no-profit study. Our proposal aims at creating a noninvasive Horizontal Data Integration (HDI) classifier for early diagnosis of breast cancer, with the final goal of avoiding in most cases useless biopsies of suspect cases encountered during radiological screening. Women with radiologically identified lesions, BIRADS-3/4/5, smaller than …

  • 15 Mar, 2021
  • 1 location