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Found 422 clinical trials
Predict Adverse Events by Covid-19 Nephritis

This non-interventional, observational study retrospectively (and in parts prospectively) investigates, if a Covid-19 associated Nephritis, diagnosed by Urine-dipstick and further Urine-analyses on addmission, can help to predict later complications, adverse outcomes and later need for ICU-capacity in Covid-19 patients as well as can guide preventive strategies.

covid-19
  • 27 views
  • 25 Jan, 2021
  • 1 location
Circulating Osteocalcin-positive Cells in Breast Cancer Bone Metastasis

Bone metastasis (i.e. cancer cell spreading to bone) is the major clinical problem of advanced breast cancer patients. Bone metastasis is not curable nor preventable. Currently available therapeutic approaches are only palliative. The major hurdle for improving bone metastasis treatment is lack of sensitive diagnostic tools. Diagnosis of bone metastasis …

  • 0 views
  • 22 Jan, 2021
  • 2 locations
C-protein Reactive for the Detection of Anastomotic Leakage After Surgery for Digestive Cancer

The aim of this study is to investigate the diagnostic accuracy of the C Protein Reactive (CRP) for the detection of Anastomotic leakage after surgery for digestive cancer. The standard protocol in our unit is to measure the CRP on the second and fourth postoperative day. The main aim of …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Ovarium Cancer Detection by TEP's and ctDNA

Rationale: Cancer is primarily diagnosed by clinical presentation, imaging and pathological analysis of tissue biopsies, increasingly supported by molecular diagnostics tests. However, late diagnosis and misdiagnosis due to limitations of tissue biopsy acquisition remains a major problem. Therefore, a general blood test to pinpoint cancer early and adequately can be …

tumor cells
cancer of the ovary
tumor markers
  • 15 views
  • 23 Jan, 2021
  • 3 locations
Predictors of Acute Exacerbation in Patients With COPD - an Observational Study

Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by respiratory problems and poor airflow with dyspnea and cough being the main symptoms. Acute exacerbations of COPD (AECOPD) are the most important events for patients with COPD that have a negative impact on patients quality of life, accelerate disease …

pulmonary disease
dyspnea
obstructive lung disease
cough
  • 0 views
  • 24 Jan, 2021
  • 1 location
Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms

Develop a wearable sensor package to gather data on COVID-19-like signs and symptoms such as elevated body temperature, respiratory parameters, heart rate ,cough and gait. Create algorithms to monitor and track changes to COVID19-like signs and symptoms for developing a better care and isolation strategies for COVID-19 pandemic.

fever
covid-19
dyspnea
cough
  • 22 views
  • 24 Jan, 2021
  • 1 location
Pre-existing Kinase Domain Mutations in Ph-positive Leukemias

The main task of this study includes analyses of the BCR-ABL1 (breakpoint cluster region/Abelson) gene and mutations in the BCR-ABL1 tyrosine kinase domain within flow-sorted stem cells from the bone marrow and/or peripheral blood specimens. To assess the germline configuration of the patient, DNA from fingernail clippings will be investigated.

  • 0 views
  • 01 Apr, 2021
  • 1 location
NEURODEVELOPMENTAL OUTCOMES OF SINGLETON CONCEIVED FROM FRESH AND FROZEN EMBRYO TRANSFER COMPARED WITH NATURALLY CONCEIVED

This study aimed to: detect difference in neurobehavior, maturity, Apgar score and birth weight of singleton conceived from fresh and frozen embryo transfer and naturally conceived.

  • 0 views
  • 04 Mar, 2021
  • 1 location
Use of GDF15 as a Biomarker for Early Diagnosis of DM and Monitoring of Progress of Complications in Asians

Significant differences in the expression of individual Growth Differentiation Factor 15 (GDF-15) proteins among Taiwanese harboring different mitochondrial genotypes are noted, and their blood serum levels also exhibited associations with diabetes. GDF-15 was originally discovered as an autocrine regulator of macrophage activation and shown to play important roles in fibrosis, …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Characterisation of Heart Involvement in Fabry Disease With T1 Mapping

Fabry disease is a rare lysosomal storage disorder characterised by a genetic deficiency in the -galactosidase enzyme. This deficiency leads to a progressive accumulation of a fatty substance, called glycosphingolipids within a specific part of our cells called the lysosome. This lysosomal accumulation can have devastating effects on patients with …

  • 0 views
  • 03 Feb, 2021
  • 1 location