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Found 14 clinical trials
  • 3 views
  • 24 Jan, 2021
  • 1 location
Very Large Sizes in Adolescents : Tibial and Femoral EPIphysiodesis

The very large sizes can be very disabling and at the origin of a difficult psychological experience. Some families are in demand for a growth-curbing treatment. Currently, only hormonal treatments are offered in France but they are at the origin of many side effects. Northern European countries applied a surgical …

  • 0 views
  • 17 Mar, 2021
  • 5 locations
Efficacy and Safety Study of Triptorelin 3-Month Formulation in Chinese Children With Central Precocious Puberty.

The purpose of this study is to observe whether the Triptorelin pamoate 15mg (3-month formulation) effectiveness in Chinese population of CPP children has the same or similar trend with that in overseas CPP population. This is measured by assessing the proportion of children who have a suppressed Luteinizing Hormone (LH) …

  • 0 views
  • 14 Apr, 2021
  • 8 locations
Pharmacokinetic Study of Leuprolide Acetate Injectable Suspension in the Treatment of Central Precocious Puberty

Exploring the efficacy in Leuprolide 45mg in slowing down or reversing Central Precocious Puberty in girls ages 2-8 and boys ages 2-9.

  • 0 views
  • 08 Nov, 2020
  • 1 location
Analysis of Genetic and Environmental Parameters Influencing Growth Rate of Precocious Puberty Children

The goal of CPP-EDG 01 study is to assess possible genetic and/or environmental parameters which may influence the growth rate of children affected by precocious puberty. In this view, we

sex hormones
precocious puberty
central precocious puberty
triptorelin
leuprolide
  • 8 views
  • 07 Nov, 2020
  • 1 location
Ovarian Contribution to Androgen Production in Adolescent Girls

active during early puberty. The purpose of this study is to determine how the ovaries contribute to the production of male hormones in the body during different stages of puberty, so that it can be

testosterone level
androgens
follicle stimulating hormone
prolactin
polycystic ovary syndrome
  • 37 views
  • 27 Jan, 2021
  • 1 location
The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's

The LUCINDA Trial is a three-site, phase II, randomized, double-blind, placebo-controlled study of leuprolide acetate (Eligard) in women with Alzheimer's Disease taking a stable dose of donepezil (Aricept.) Its objective is to assess the efficacy of a 48-week regimen of leuprolide (22.5 mg per 12 weeks) compared to placebo on …

dementia
mini-mental state examination
aricept
alzheimer's disease
donepezil
  • 41 views
  • 15 Mar, 2021
  • 3 locations
Evaluation of Adrenal Androgens in Normal and Obese Girls After Suppression and Stimulation

Women with polycystic ovary syndrome (PCOS) often have irregular menstrual periods, too much facial and body hair, and weight gain. Women with PCOS also have a hard time becoming pregnant. Girls with high levels of the male hormone testosterone often develop PCOS as adults. Some girls with high levels of …

testosterone level
androgens
follicle stimulating hormone
prolactin
polycystic ovary syndrome
  • 132 views
  • 26 Jan, 2021
  • 1 location
Overweight and Obesity and Puberty Development Cohort Study

Precocious puberty and childhood overweight and obesity are important public health problems that both had adverse effects, which including psychological symptom in childhood, short final height

overweight and obesity
precocious puberty
  • 6 views
  • 23 Jan, 2021
  • 1 location
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders

(IHH), precocious (early) puberty, and delayed puberty. Individuals do not have to travel to Boston to participate in this study.

secondary hypogonadism
precocious puberty
hypogonadism
hormone levels
idiopathic hypogonadotropic hypogonadism
  • 161 views
  • 26 Jan, 2021
  • 1 location