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Found 353 clinical trials
Featured trial
Diverse VCID "Vascular Cognitive Impairment and Dementia"

The nationwide, NIH-sponsored, Diverse Vascular Contributions to Cognitive Impairment and Dementia (DVCID) Study aims to investigate how vascular health and abnormal white matter signals in the brain affect thinking in three patient populations, namely Caucasian, African American, and Hispanic/Latino. The presence of white matter signals (white matter hyperintensities) shows that …

Accepts healthy volunteers
  • 7 views
  • 18 May, 2023
  • 9 locations
Featured trial
Alzheimer’s Disease Research Center (ADRC) Longitudinal Study

over the age of 65, as a comparison. The study will follow the progression of various dementias to help with early detection, accurate diagnosis, and options for targeted treatments.

mild cognitive impairment
cancer
depression
Accepts healthy volunteers
cognitive impairment
  • 218 views
  • 25 Jan, 2022
  • 1 location
Featured trial
Digital biomarkers for Alzheimer's Disease with compact dual-mode brain sensing

The research team is conducting a research study to find biological signs in the brain for early detection of Alzheimer’s Disease (AD) with a new low-cost, portable device. This study plans to

Accepts healthy volunteers
  • 0 views
  • 28 Mar, 2023
  • 1 location
Featured trial
Mild Cognitive Impairment

to be more helpful. If these efforts are successful, we may be able to more effectively treat or even halt the progression of Alzheimer’s disease. Early detection and research discovery provide hope

mild cognitive impairment
alzheimer's disease
cognitive impairment
progression of alzheimer's disease
dementia
  • 13 views
  • 30 Jul, 2021
  • 1 location
Early Detection of GEnetic Risk (EDGE)

The study intervention involves having patients complete a familial cancer risk assessment survey. Those who are found to be at high risk will be offered genetic testing for a panel of hereditary cancers. A "previvor" plan will be created to assist patients and their providers in completing the appropriate follow-up …

Accepts healthy volunteers
  • 27 views
  • 11 Mar, 2022
  • 2 locations
Research on Key Technologies and System Optimization of Early Warning and Resuscitation of Cardiac Arrest

including early warning, early detection and first aid of cardiac arrest. Aortic balloon occlusion can significantly improve the effectiveness of cardiopulmonary resuscitation. Transesophageal and CRRT

  • 0 views
  • 18 Jul, 2021
  • 1 location
Digital Detection of Dementia (D Cubed) Studies (Dcubed)

The specific aim of the pragmatic trial is to evaluate the practical utility and effect of the PDM, the QDRS, and the combined approach (PDM + QDRS) in improving the annual rate of new documented ADRD diagnosis in primary care practices.

  • 0 views
  • 07 Oct, 2022
  • 1 location
"HerzCheck" - Detection of Early Heart Failure Using Telemedicine in Structurally Weak Regions

This study is intended to provide a basis for decision-making for the improved medical care of patients with asymptomatic heart failure, especially in structurally weak regions.

  • 0 views
  • 08 Dec, 2021
  • 1 location
A Study of Guselkumab and Golimumab Combination Therapy in Participants With Active Psoriatic Arthritis (AFFINITY)

The purpose of this study is to evaluate the efficacy of guselkumab plus golimumab combination treatment in participants with active psoriatic arthritis (PsA) and inadequate response (IR) to prior anti-tumor necrosis factor-alpha (anti-TNF-alpha) therapies by assessing clinical response compared with guselkumab monotherapy.

polyarticular arthritis
biosimilar
tumour necrosis
arthritis mutilans
golimumab
  • 17 views
  • 08 Apr, 2023
  • 36 locations
CogMe for the Prevention and Early Detection of Delirium (CogMe)

This study is designed as a prospective interventional study to evaluate the CogMe system for early detection and prevention of delirium. The study will collect physiological and cognitive

  • 0 views
  • 19 Apr, 2022
  • 1 location