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Found 19 clinical trials
Fast-track Blood Test for Suspected Fever by Deficiency of a Kind of White Blood Cells As Main Defense Against Infection (FRANCiS-NF)

This is a comparative study for adult participants with cancer who are suspected to have neutropenic fever (or fever with low neutrophil count) in emergency department. Neutrophil is a kind of defensive white blood cell combating against infection, especially by bacteria and fungi. Low neutrophil can be part of the …

  • 0 views
  • 11 Jul, 2022
  • 1 location
Effect of Montelukast Versus Co Enzyme in Sepsis

Sepsis is a leading cause of morbidity and mortality in intensive care units. Sepsis is a life-threatening organ dysfunction linked to a dysregulated host response to infection. It leads to

antibiotics
fever
antioxidants
cytokines
meropenem
  • 0 views
  • 10 Apr, 2022
Safety and Efficacy of HA380 Hemoadsorption in Patients With Septic Shock

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Intensive care unit (ICU) mortality in patients with septic shock and acute kidney

renal replacement therapy
hemodiafiltration
  • 0 views
  • 20 Aug, 2021
  • 1 location
Intravenously Administered M6229 in Critically Ill Sepsis Patients (HistoSeps)

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Mortality is high and survivors frequently suffer from long-term sequelae. Extracellular

shock
dysregulated host response
heparin
septic shock
  • 0 views
  • 23 Apr, 2022
  • 1 location
Non-Invasive Cardiometry and Ultrasound Guided Inferior Vena Cava Collapsibility Index in Assessing Fluid Responsiveness

43 patients between 18-60 years presenting with criteria of sepsis (life-threatening organ dysfunction caused by a dysregulated host response to infection, suspected or documented infection and

Accepts healthy volunteers
  • 0 views
  • 11 Nov, 2021
  • 1 location
Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. It is the most expensive healthcare condition to treat in United States and has a mortality rate

systolic blood pressure
severe sepsis
organ failure
sepsis
resuscitation
  • 0 views
  • 26 Jan, 2021
  • 1 location
Erythromycin in Septic Patients: Immunomodulatory Role and Clinical Impact

In sepsis and septic shock, the host response is characterized by a complex of immune-inflammatory reactions; triggered and activated by microbial components. These reactions are controlled by a balance of pro-inflammatory cytokines and anti-inflammatory cytokines. The imbalance of this immune response is a source of organ dysfunction; major prognostic factor …

shock
procalcitonin
pneumonia
septic shock
cytokines
  • 0 views
  • 11 May, 2022
  • 1 location
Emergency Echocardiography in Sepsis (GENESIS)

Acute circulatory failure that combines hypovolemia, vasoplegia and cardiac dysfunction plays a major role in the development of sepsis-related organ dysfunction. Pathophysiological mechanisms are multiple and complex. The objective of the GENESIS study is to determine the impact of early haemodynamic assessment using echocardiography in association with a therapeutic algorithm …

shock
systolic blood pressure
crystalloid
organ failure
resuscitation
  • 0 views
  • 11 Jul, 2022
  • 7 locations
Personalized Immunotherapy in Sepsis (ImmunoSep)

Αim of ImmunoSep is to assess whether personalized adjunctive immunotherapy directed against a state of either fulminant hyper-inflammation or immunoparalysis is able to change sepsis outcomes. Patients will be selected by a panel of biomarkers and laboratory findings and will be allocated to placebo or immunotherapy treatment according to their …

pneumonia
bacteremia
organ failure
  • 0 views
  • 04 Oct, 2022
  • 21 locations
Diagnostic Accuracy in Sepsis

The sepsis syndrome has recently been more stringently defined as "a life-threatening organ dysfunction caused by a dysregulated host response to infection". Clinical and paraclinical tools are

sepsis
dysregulated host response
  • 0 views
  • 14 May, 2022
  • 1 location