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Found 767 clinical trials
Pulmonary Function Using Non-invasive Forced Oscillometry (PUFFOR)

dysplasia, transient tachypnea of the newborn, meconium aspiration syndrome, and response to treatments given to newborn infants with lung diseases using a non-invasive airway oscillometry system.

respiratory distress
continuous positive airway pressure
transient tachypnea of the newborn
pulmonary disease
Accepts healthy volunteers
  • 05 Apr, 2022
  • 1 location
PEER Trial: Part 2

reliability of a multimodal optical imaging system to detect cervical dysplasia, with the gold reference standard of histopathology.

cancer screening
hpv test
cervical cancer screening
cervical dysplasia
  • 19 Jun, 2022
  • 4 locations
Multimodal Imaging for Surveillance in Patients With Oral Potentially Malignant Disorders

This early phase I trial studies how well multimodal imaging works for surveillance in patients with oral potentially malignant disorders. New types of imaging devices may help doctors decide if a lesion in the mouth is pre-cancerous or cancerous.

oral cancer
high-resolution microendoscopy
multimodal imaging
  • 23 Feb, 2022
  • 1 location
SUrveillance of PREMalignant Stomach - Individualized Endoscopic Follow-up (SUPREME)

Introduction: Gastric atrophy and intestinal metaplasia are the principal precursors for gastric cancer and, therefore, are considered gastric premalignant conditions. Although current guidelines recommend surveillance of individuals with these conditions, the best method for its identification and staging (histological vs endoscopy) and the best time schedule for follow-up are still …

  • 21 Apr, 2022
  • 1 location
Health Information Technology System ("Roadmap 2.0") in the Context of Hematopoietic Cell Transplantation

The purpose of this research study is to measure the effects of using a mobile phone app (Roadmap 2.0) on the health-related quality of life of caregivers and patients undergoing allogeneic/autologous hematopoietic cell transplantation (HCT).

cell transplantation
  • 25 Mar, 2022
  • 2 locations
Cervical Cancer Screening by Self-sampling in a Cohort of Younger Women in Ethiopia

(CIN). To assess how specific cervicovaginal microbiota compositions are associated with HPV infection, cervical dysplasia, and cancer

cancer screening
cervical intraepithelial neoplasms
human papilloma virus vaccine
cervical dysplasia
cervical cancer screening
  • 24 Nov, 2021
  • 1 location
Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.

This is a phase I/Ib, open label study. The escalation portion will characterize the safety and tolerability of DKY709 and DKY709 in combination with PDR001 in subjects with NSCLC or melanoma who have received prior anti-PD-1/PD-L1 therapy, or subjects with NPC. After the determination of the MTD/RD for a particular …

programmed cell death 1 ligand 1
core needle biopsy
solid tumour
  • 06 Jun, 2022
  • 8 locations
PREACT Study: Locally Advanced Gastric Cancer, Chemoradiotherapy vs. Chemotherapy Followed by D2 Surgery and Adjuvant Chemotherapy (PREACT)

Although the incidence of gastric cancer has been substantially declining for several decades, it is still the sixth most common cancer and the fourth most frequent cause of cancer death worldwide. Surgery is still the only curative option for gastric cancer. However, most patients are unable to undergo surgery because …

neutrophil count
cancer chemotherapy
  • 24 Feb, 2022
  • 1 location
Reduced vs Conventional Dosage Intensity-modulated Radiotherapy for Chemotherapy-sensitive Stage II-III Nasopharyngeal Carcinoma

Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that radiotherapy with reduced dose could significantly reduce the incidence of radiotherapy toxicities, improve the quality of life of patients while ensuring the tumor control rates for NPC patients staged as II-III who are sensitive to induction chemotherapy (imaging evaluation …

induction chemotherapy
nasopharyngeal carcinoma
epstein-barr virus dna
administration intravenous
  • 25 Jan, 2021
  • 6 locations
Two-stage Cervical Cancer Screening Algorithms Using Primary hrHPV Testing in Botswana

of high-grade cervical dysplasia, using histology as the gold standard. We will validate the AmpFire Assay for hrHPV self-testing in our setting. We also seek to understand in-depth the attitudes

cancer screening
diagnostic procedures
cervical cancer stage
cervical cancer screening
human papilloma virus vaccine
  • 19 Sep, 2021
  • 1 location