Found 258 clinical trials
Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic Disease (PACI) Initiative
Background: Cardiometabolic diseases are medical disorders that can occur together and affect the heart. They increase the risk of developing heart disease and diabetes. One disorder, psoriasis, is an inflammation that mostly affects the skin but can affect the entire body. Another disorder, atherosclerosis, is a process in which cholesterol …
- 123 views
- 23 Nov, 2020
- 1 location
Inflammatory Characterization of Known or Possible Cardiovascular Diseases
Background: Cardiometabolic diseases are a combination of medical disorders that, when they occur together, increase the risk of heart disease and diabetes. Researchers want to learn if there is a relationship between these diseases and inflammation (redness, swelling, and pain). Inflammation affects the entire body. Researchers will study this relationship …
- 167 views
- 23 Nov, 2020
- 1 location
High Cholesterol
We are seeking participants for a clinical research study to evaluate the impact of an investigational medication for adults with high cholesterol and are taking a statin [Atorvastatin (Lipitor), Fluvastatin (Lescol), Lovastatin (Altoprev), Pravastatin (Pravachol), Rosuvastatin (Crestor), Simvastatin (Zocor), Pitavastatin (Livalo)]. Cardiovascular risk is still high for individuals who are …
- 0 views
- 11 Aug, 2022
- 1 location
FOURIER - Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk
FOURIER - Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk
- 270 views
- 25 Mar, 2021
- 1 location
A Phase 2 Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of ARO-APOC3 in Adults With Dyslipidemia
This is an open-label extension of the parent studies AROAPOC3-2001 and AROAPOC3-2002. Adult participants with dyslipidemia who completed the blinded 12-month period from either parent study and
- 0 views
- 19 Sep, 2022
- 4 locations
Study of ARO-APOC3 in Adults With Mixed Dyslipidemia (MUIR)
Participants who have met all protocol eligibility criteria will be randomly assigned to treatment (ARO-APOC3 or placebo) in a double-blind fashion and will be evaluted for safety and efficacy over 48 weeks. Participants will be counseled to remain on a specified diet throughout the study, as recommended by the Investigator …
- 0 views
- 04 Oct, 2022
- 31 locations
Italian Digital Primary Cardiovascular Prevention Study (CV-PREVITAL)
The CV-PREVITAL study is a randomised clinical trial (RCT) controlled versus usual-care designed to compare the effectiveness of a mobile health (mHealth) intervention with that of usual care in reducing specific cardiovascular (CV) risk factors (in the short term) and the occurrence of vascular events (in the long term). Promoted …
- 0 views
- 04 Oct, 2022
- 29 locations
A Dose-response Study of Dietary Resveratrol on Lipid Metabolism Disorder
In order to study the effect of resveratrol on the improvement of lipid metabolism, randomized intervention trials were conducted to compare the effects of resveratrol on the improvement of lipid metabolism in different dose groups. To explore the best dose of resveratrol for the prevention and treatment of metabolic diseases …
- 0 views
- 05 Oct, 2021
- 1 location
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects
This study will assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of AZD0780 following single and multiple dose administration to healthy subjects with or without elevated Low-Density Lipoprotein-Cholesterol (LDL-C) levels. This study will consist of two parts (Parts A and B). 56 subjects have been planned for Part A …
- 0 views
- 13 Jul, 2022
- 1 location
Efficacy and Safety of Cipros 20 Association on Dyslipidemia Treatment
The purpose of this study is to evaluate the efficacy of Cipros 20 association in the treatment of dyslipidemia treatment.
- 0 views
- 04 Oct, 2022
- 1 location