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Found 258 clinical trials
Featured trial
Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic Disease (PACI) Initiative

Background: Cardiometabolic diseases are medical disorders that can occur together and affect the heart. They increase the risk of developing heart disease and diabetes. One disorder, psoriasis, is an inflammation that mostly affects the skin but can affect the entire body. Another disorder, atherosclerosis, is a process in which cholesterol …

heart disease
cholesterol measurement
atherosclerosis
diabetes
  • 123 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Inflammatory Characterization of Known or Possible Cardiovascular Diseases

Background: Cardiometabolic diseases are a combination of medical disorders that, when they occur together, increase the risk of heart disease and diabetes. Researchers want to learn if there is a relationship between these diseases and inflammation (redness, swelling, and pain). Inflammation affects the entire body. Researchers will study this relationship …

heart disease
fats
diabetes
  • 167 views
  • 23 Nov, 2020
  • 1 location
Featured trial
High Cholesterol

We are seeking participants for a clinical research study to evaluate the impact of an investigational medication for adults with high cholesterol and are taking a statin [Atorvastatin (Lipitor), Fluvastatin (Lescol), Lovastatin (Altoprev), Pravastatin (Pravachol), Rosuvastatin (Crestor), Simvastatin (Zocor), Pitavastatin (Livalo)]. Cardiovascular risk is still high for individuals who are …

body mass index
pravastatin
hmg-coa reductase inhibitors
atorvastatin
cholesterol level
  • 0 views
  • 11 Aug, 2022
  • 1 location
Featured trial
FOURIER - Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk

FOURIER - Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk

  • 270 views
  • 25 Mar, 2021
  • 1 location
A Phase 2 Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of ARO-APOC3 in Adults With Dyslipidemia

This is an open-label extension of the parent studies AROAPOC3-2001 and AROAPOC3-2002. Adult participants with dyslipidemia who completed the blinded 12-month period from either parent study and

  • 0 views
  • 19 Sep, 2022
  • 4 locations
Study of ARO-APOC3 in Adults With Mixed Dyslipidemia (MUIR)

Participants who have met all protocol eligibility criteria will be randomly assigned to treatment (ARO-APOC3 or placebo) in a double-blind fashion and will be evaluted for safety and efficacy over 48 weeks. Participants will be counseled to remain on a specified diet throughout the study, as recommended by the Investigator …

  • 0 views
  • 04 Oct, 2022
  • 31 locations
Italian Digital Primary Cardiovascular Prevention Study (CV-PREVITAL)

The CV-PREVITAL study is a randomised clinical trial (RCT) controlled versus usual-care designed to compare the effectiveness of a mobile health (mHealth) intervention with that of usual care in reducing specific cardiovascular (CV) risk factors (in the short term) and the occurrence of vascular events (in the long term). Promoted …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 29 locations
A Dose-response Study of Dietary Resveratrol on Lipid Metabolism Disorder

In order to study the effect of resveratrol on the improvement of lipid metabolism, randomized intervention trials were conducted to compare the effects of resveratrol on the improvement of lipid metabolism in different dose groups. To explore the best dose of resveratrol for the prevention and treatment of metabolic diseases …

Accepts healthy volunteers
  • 0 views
  • 05 Oct, 2021
  • 1 location
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects

This study will assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of AZD0780 following single and multiple dose administration to healthy subjects with or without elevated Low-Density Lipoprotein-Cholesterol (LDL-C) levels. This study will consist of two parts (Parts A and B). 56 subjects have been planned for Part A …

Accepts healthy volunteers
cholesterol level
  • 0 views
  • 13 Jul, 2022
  • 1 location
Efficacy and Safety of Cipros 20 Association on Dyslipidemia Treatment

The purpose of this study is to evaluate the efficacy of Cipros 20 association in the treatment of dyslipidemia treatment.

  • 0 views
  • 04 Oct, 2022
  • 1 location