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Found 448 clinical trials
Featured trial
Episodic Migraine: Phase 3 Study of BOTOX (Botulinum Toxin Type A) for the Prevention of Migraine in Subjects with Episodic Migraine

The purpose of this study is to see if the study drug, BOTOX®, is safe and helps prevent episodic migraines in adults that experience 6-14 migraine days per month and less than 15 headache days per month. This study is for research purposes only. This study will help the sponsor, …

  • 21 Apr, 2022
  • 1 location
Featured trial
COMMANDS - Myelodysplastic Syndromes (MDS) - ACE536-MDS-002 – Canada  

The study will be conducted in compliance with the International Council for Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements.   This is an interventional active-controlled, open-label, randomized Phase 3 study to compare the efficacy and safety of luspatercept …

epoetin alfa
  • 04 May, 2022
  • 10 locations
Unplugged, a Drug Use Prevention Program: Adaptation and Evaluation of Effectiveness Among Students in Chile (YSLQQ)

Substance use and drug related disorders are important public health problems. Alcohol and illicit drug use account for 5.4% of the total burden of disease and the peak has been found in early

Accepts healthy volunteers
  • 24 Feb, 2022
  • 1 location
Patient Decision Aid for Opioid Use Disorder

by rural vs. non-rural areas) for adults with OUD. Patient outcomes will be tracked by (1) personal assessments (baseline, 3 months, and 6 months): drug use, overdose, healthcare utilization, and (2

narcotic use
substance use
drug use
  • 24 Nov, 2021
  • 1 location
Preventing Retaliatory Gun Violence in Violently Injured Adults

understand if the violence intervention affects other behaviors, such as firearm use, drug use, aggression, risky behaviors, and rates of violent re-injury.

  • 14 Aug, 2021
  • 1 location
Implementing Alcohol Misuse SBIRT in a National Cohort of Pediatric Trauma Centers (IAMSBIRT)

implementation of SBIRT for alcohol and other drug use in pediatric trauma centers. Our implementation strategy is based on the Science to Service Laboratory (SSL), an approach developed by the SAMHSA-funded

  • 02 Mar, 2022
  • 1 location
Behavioral Economic and Wellness-based Approaches for Reducing Alcohol Use and Consequences Among Emerging Adults

The purpose of this study is to evaluate an intervention approach for non-student emerging adults that attempts to reduce alcohol use by decreasing stress and increasing engagement in positive and goal-directed activities that provide meaningful alternatives to alcohol use.

  • 25 Mar, 2022
  • 1 location
Individualized Administration of Warfarin by Polymorphisms of VKORC1 and CYP2C9 Genes

The purpose of this study is to explore the individualized administration model of warfarin suitable for Chinese people, and provide a scientific reference for the use of warfarin to Chinese people.

  • 22 Jan, 2021
  • 1 location
Brief Intervention to Reduce STDs in ER Drug Users - 1

The purpose of this study is to test whether a brief motivational interview focused on sexual practices will facilitate behavior change, risk reduction and reduced rate of sexually transmitted infections among emergency department patients who use heroin and cocaine and are out-of-treatment for their substance abuse.

motivational interviewing
  • 07 Nov, 2020
  • 1 location
Families Talking Together Plus: An Approach to Promote Sexual Delay and Strengthen Sexual Risk Avoidance Education (FTT+)

Despite reductions in adolescent sexual behavior over the past decade, premature sexual activity remains prevalent among adolescents and alarming adolescent sexual and reproductive health (SRH) disparities exist. Positive youth development (PYD) research has identified adolescent protective factors, such as success sequencing, self-regulation, goal setting, and strong family support [i.e., positive …

Accepts healthy volunteers
  • 14 May, 2022
  • 1 location