Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 67 clinical trials
None
Study of AZD0466 Monotherapy or in Combination in Patients With Advanced Haematological Malignancies

to assess drug-drug interaction (DDI) potential between AZD0466 and the azole antifungal voriconazole.

  • 0 views
  • 19 Jan, 2022
  • 31 locations
None
An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

The purpose of this study is to evaluate the objective response rate (complete response [CR]+ partial response [PR]) of the selected dose regimen in participants with metastatic or surgically unresectable urothelial cancers that harbor specific FGFR genomic alterations.

renal function
erdafitinib
dose regimen
measurable disease
adjuvant chemotherapy
  • 40 views
  • 09 Dec, 2021
  • 159 locations
None
Evaluating the Pharmacokinetics and Drug Interaction Potential of the Botanical Dietary Supplement Cinnamon

The purpose of this study is to evaluate a well-characterized, commercially available cinnamon dietary supplement as a precipitant of pharmacokinetic interactions with CYP2A6 substrates in healthy volunteers. Nicotine gum will be used as the CYP2A6 probe drug (i.e., positive control) and letrozole as a high-impact object drug. Results will be …

Accepts healthy volunteers
  • 3 views
  • 28 Dec, 2021
  • 1 location
None
Drug-drug Interaction Study With GLPG4716 and Nintedanib and Pirfenidone in Healthy Subjects

The main aim of this study is to investigate the possible effect of GLPG4716 on the pharmacokinetics (PK) of pirfenidone and nintedanib. Further aims are to investigate safety and tolerability of GLPG4716 alone or administered simultaneously with pirfenidone or nintedanib.

Accepts healthy volunteers
  • 0 views
  • 11 Nov, 2021
  • 1 location
None
  • 0 views
  • 15 Dec, 2021
  • 2 locations
None
Clinical Trial of Lurbinectedin (PM01183) in Patients With Advanced Solid Tumors

Prospective, open-label, two-way crossover, phase Ib drug-drug interaction study in patients with advanced solid tumors

  • 0 views
  • 07 Oct, 2021
  • 2 locations
None
A Study to Assess the Effects of Itraconazole Rifampicin and Omeprazole on Pharmacokinetics of Adavosertib

This is a Phase 1, open-label, non-randomised, 3-arm (A, B, and C), drug-drug interaction study in patients with advanced solid tumours.

  • 0 views
  • 19 Jan, 2022
  • 8 locations
None
A Study to Evaluate the Safety Tolerability and Pharmacokinetics of KRP-A218 in Healthy Subjects

-A218, including food-effect. In Part C, the drug-drug interaction (DDI) with itraconazole will be evaluated.

Accepts healthy volunteers
  • 0 views
  • 19 Nov, 2021
  • 2 locations
None
Study of PBI-0451 in Healthy Subjects.

also to explore drug-drug interaction potential of PBI-0451.

Accepts healthy volunteers
  • 58 views
  • 19 Jan, 2022
  • 1 location
None
The Effect of Sirolimus on the Pharmacokinetics of Tacrolimus

The purpose of this study is to understand whether the pharmacokinetics of tacrolimus is influenced by the concurrent use of sirolimus.

sirolimus
mycophenolate
tacrolimus
  • 3 views
  • 07 Nov, 2020
  • 1 location