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Found 40 clinical trials
A Study to Evaluate a New Way to Identify/Diagnose Tumours With Somatostatin Receptors Using [68]Ga-HA-DOTATATE and to Ensure it is Safe to Use

A [68]Ga-HA-DOTATATE PET/CT or PET/MRI scan is a nuclear medicine test used to create pictures of the whole body that will show where somatostatin receptors are found, including on tumours

dotatate
gastrin
paraganglioma
chromogranin a
5-hydroxyindoleacetic acid
  • 0 views
  • 28 Feb, 2022
  • 1 location
A Clinical Study to Assess the Combination of Two Drugs (177Lu-DOTATATE and Nivolumab) in Neuroendocrine Tumours

This is a prospective, multi-centre, open-label, single-arm, stratified, exploratory, Phase 2 study evaluating the efficacy and safety of 177Lu-DOTATATE in combination with nivolumab in adult

dotatate
lu-dota-tate
hysterectomy
tubal ligation
measurable disease
  • 0 views
  • 25 Jan, 2021
  • 5 locations
Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Patients With Ectopic Cushing Syndrome

-DOTATATE-PET, to localize the source of ectopic ACTH production. The study also examines whether administration of the glucocorticoid antagonist mifepristone can improve the sensitivity of the (68)Ga

ct scan
mifepristone
dotatate
ectopic acth
pituitary
  • 17 views
  • 12 May, 2022
  • 1 location
Gallium-68 NODAGA-JR11 PECT/CT in Neuroendocrine Tumors

NODAGA-JR11 is a novel somatostatin receptor antagonist, while Gallium-68 DOTATATE is a typical somatostatin receptor agonist. This study is to evaluate the lesion detection ability of Gallium

  • 0 views
  • 26 Jul, 2021
  • 2 locations
Telotristat With Lutathera in Neuroendocrine Tumors

This trial will test the hypothesis that Telotristat treatment increases the antitumor efficacy of Lutetium Lu 177 Dotatate therapy in neuroendocrine tumors (NETs).

  • 0 views
  • 10 Oct, 2021
  • 1 location
PET Imaging of Inflammation and Lipid Lowering Study

While 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging has been used as an early marker of drug efficacy in numerous clinical cardiovascular drug trials, as a glucose analog, its signal in the vasculature lacks inflammatory cell-specificity. Moreover, high background 18F-FDG signals from the myocardium often preclude coronary artery imaging, despite …

cholesterol level
18f-fdg
pcsk9
acute coronary syndrome
cholesterol measurement
  • 0 views
  • 30 Aug, 2021
  • 1 location
Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation Therapy

This phase II trial studies how well lutathera works in treating patients with meningioma that cannot be treated with surgery (inoperable) and is growing, spreading, or getting worse (progressive) after external beam radiation therapy. Lutathera is a radioactive drug administered in the vein that is designed to target and kill …

  • 5 views
  • 22 Mar, 2022
  • 1 location
Molecular-Guided Surgery for Pancreatic and GI Neuroendocrine Cancers

The purpose of this study is to see if the use of 68Gallium- positron emission tomography and computer tomography (PET/CT) scans along with NETSPOT (Advanced Accelerator Applications USA, Inc.) can better define the localization of Neuroendocrine tumors enhancing the surgical removal of Neuroendocrine tumors (NETs).

dotatate
positron emission tomography
neuroendocrine tumor
cancer
pet/ct scan
  • 0 views
  • 04 Sep, 2021
  • 1 location
Pembrolizumab With Liver-Directed or Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors and Liver Metastases

This pilot phase II trial studies how effective pembrolizumab and liver-directed therapy or peptide receptor radionuclide therapy are at treating patients with well-differentiated neuroendocrine tumors and symptomatic and/or progressive tumors that have spread to the liver (liver metastases). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

dotatate
radionuclide therapy
international normalized ratio
platelet count
measurable disease
  • 15 views
  • 27 Feb, 2022
  • 1 location
Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers (FAPI PET RDRC)

This exploratory study investigates how an imaging technique called 68Ga-FAPi-46 PET/CT can determine where and to which degree the FAPI tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues in patients with cancer. Because some cancers take up 68Ga-FAPi-46 it can be seen with PET. FAP stands for Fibroblast Activation Protein. …

ct scan
dotatate
bladder tumor
cholangiocarcinoma
carcinoma
  • 0 views
  • 21 Apr, 2022
  • 1 location