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Found 94 clinical trials
Standard Versus Radiobiologically-Guided Dose Selected SBRT in Liver Cancer

Radiation is a standard treatment option for patients with liver cancer. Unfortunately, the tumour grows after radiation in many patients and radiation can harm normal tissues. A new treatment using a specialized radiation procedure called Stereotactic body radiotherapy (SBRT) may increase the chance to control liver cancer and reduce the …

cancer
  • 0 views
  • 17 Sep, 2021
  • 1 location
Nitrous Oxide as Treatment for Fibromyalgia

The purpose of this study is to explore a potential role of nitrous oxide in treating pain associated with fibromyalgia.

Accepts healthy volunteers
sham treatment
  • 0 views
  • 10 May, 2022
  • 1 location
Viral Infection in Asthma (VIA) Study (VIA)

Often when people with asthma get a virus caused by the common cold (rhinovirus), they also experience an increase or worsening of their asthma symptoms. The purpose of this study is to see if the study medication dupilumab helps prevent those with mild to moderate asthma from having increased asthma …

  • 0 views
  • 05 Jun, 2022
  • 1 location
Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED

In the situation when intravenous access is not readily available or unobtainable, sub-dissociative dose ketamine can be administered via intranasal route (IN). The data supporting intranasal route in pediatric patients is somewhat conflicting with regards to the optimum intranasal dose (range 0.75-1 mg/kg) and frequencies of administration. Hence, another non-invasive …

analgesia
acute pain
postoperative pain
ketamine
analgesics
  • 24 views
  • 23 Apr, 2022
  • 1 location
  • 0 views
  • 18 Sep, 2022
Comparison Between 2-dose Versus 3-dose Regimens of Heplisav B in Cirrhosis

Investigators want to compare the seroconversion rates between two-dose and three-dose regimens of the hepatitis B vaccine (Heplisav B) among patients with cirrhosis, a randomized prospective study.

hepatitis
cirrhosis
  • 0 views
  • 07 Oct, 2022
  • 1 location
Different Initial Insulin Dose Regimens on Time to Achieve Glycemic Targets and Treatment Safety in SIIT

To compare the effects of different initial insulin dose regimens during the short-term insulin intensive treatment on time to glycemic goal, hypoglycemia prevalence, glycemic variability and other safety problems in newly diagnosed type 2 diabetes mellitus(T2DM) patients, in order to investigate the rational of formula based initiation regimen.

body mass index
hypoglycemia
oral hypoglycemic
fasting
type 2 diabetes mellitus
  • 0 views
  • 26 Oct, 2021
  • 1 location
Evaluation of Propofol Dosing Based on Total Body Weight Using Closes-loop Anaesthesia Delivery System

The pharmacokinetic profile of various drugs is altered in obese patients especially those administered by the intravenous route. Propofol is the commonly used intravenous anesthetic agent for induction and maintenance of anaesthesia as part of total intravenous anaesthesia (TIVA) regimen. A major concern with propofol dosing based on total body …

tiva
intravenous anesthetics
propofol
induction of general anesthesia
  • 0 views
  • 13 May, 2022
  • 1 location
Pembrolizumab in Association With the IMA950/Poly-ICLC for Relapsing Glioblastoma (IMA950-106)

Monocentric randomized phase I/II trial, including 24 patients diagnosed with relapsing glioblastoma (GBM) irrespective of MGMT and IDH gene status. Following diagnosis of relapsing glioblastoma by either brain CT scan or MRI, patients will be randomized in 2 arms: Arm 1: IMA950 mixed with Poly-ICLC administered subcutaneously Arm 2: Pembrolizumab …

poly iclc
dexamethasone
measurable disease
  • 48 views
  • 01 Feb, 2022
  • 1 location
Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular Degeneration (FALCON)

The purpose of this study is to evaluate the efficacy and safety of two different brolucizumab 6 mg dosing regimens in patients with visual impairment due to age-related macular degeneration (AMD) who have previously received anti-VEGF (vascular endothelial growth factor) treatment.

corrected visual acuity
edema
angiography
retinal angiomatous proliferation
vascular endothelial growth factor
  • 0 views
  • 04 Oct, 2022
  • 29 locations