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Found 170 clinical trials
Solriamfetol in Binge Eating Disorder

The goal of this project is to evaluate the efficacy and tolerability of the novel dopamine and norepinephrine reuptake inhibitor (DNRI) solriamfetol in the treatment of binge eating disorder

  • 0 views
  • 23 Mar, 2022
  • 1 location
Brain Dopaminergic Signaling in Opioid Use Disorders

Background The chemical messenger dopamine carries signals between brain cells. It may affect addiction. Heavy use of pain medicines called opioids may decrease

dopamine
methadone
toxicology screen
narcotic use
naltrexone
  • 587 views
  • 17 Jun, 2022
  • 1 location
Nefopam for Post Video-Assisted Thoracoscopic Lobectomy

block. However, for VATs, the invasive pain control somehow are too invasive. Nefopam is non-opioid painkilling medication, Serotonin, norepinephrine, dopamine reuptake inhibitor. Many study were

Accepts healthy volunteers
  • 0 views
  • 22 Apr, 2022
  • 1 location
Effects of Lactobacillus Plantarum PS128 on the Parkinsonian Symptoms in Parkinson's Disease.

This RCT study is designed to examine the extent to which L. plantarum PS128 can improve symptoms in PD patients. L. plantarum PS128 is a psychobiotic that regulates the level of dopamine in

dopamine
Accepts healthy volunteers
  • 2 views
  • 25 Jan, 2022
  • 1 location
[18F]F-DOPA Imaging in Patients With Autonomic Failure

these biomarkers may be related to the neurotransmitter dopamine (DA) and related changes in the substantia nigra (SN) and brainstem. [18F]F-DOPA is a radiolabeled substrate for aromatic amino acid

pure autonomic failure
parkinson's disease
lewy body dementia
dopamine
dementia
  • 19 views
  • 01 May, 2022
  • 1 location
Effects of Negative Affect in Individuals With Binge Eating Episodes

act rashly when distressed) often precede binge-eating. The Investigators want to answer the following questions: Can negative affect in BN and BED be linked to 1) altered dopamine related

depressed mood
self-induced vomiting
laxative
dopamine
hunger
  • 835 views
  • 26 Feb, 2022
  • 1 location
Brexpiprazole in Alcohol Use Disorder

replicated. A promising novel medication for AUD is brexpiprazole (BREX), a serotonin/dopamine activity modulator (SDAM). The investigators conducted a prior study in which the effects of another SDAM

psychiatric disorder
drug abuse
scid
functional magnetic resonance imaging
  • 388 views
  • 22 Jul, 2021
  • 1 location
Aripiprazole for Co-Morbid Schizophrenia and Cocaine Dependence

The purpose of this study is to gather systematic clinical data on whether aripiprazole, a partial dopamine agonist, beneficially affects schizophrenia plus cocaine dependence (SCHZ+CD

dopamine
perphenazine
aripiprazole
typical antipsychotic
  • 14 views
  • 07 Nov, 2020
  • 1 location
Improving Therapeutic Learning for PTSD

The proposed project seeks to demonstrate the engagement of post-exposure dopamine neurotransmission and downstream acute reorganization of dopaminergic resting-state neural networks as a means

Accepts healthy volunteers
assault
exposure therapy
sexual assault
  • 4 views
  • 25 Nov, 2021
  • 2 locations
Efficacy of N-acetylcysteine on the Craving Symptoms of Abstinent Hospitalized Patients With Cocaine Addiction

drug use. The main reason why people continue to use cocaine is because of its influence on the reward system.Indeed, this substance makes it possible to increase the level of dopamine

addiction
addicted to cocaine
drugs of abuse
dopamine
n-acetylcysteine
  • 32 views
  • 24 Jan, 2021
  • 1 location