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Found 172 clinical trials
PVP-Guided Decongestive Therapy in HF (PERIPHERAL-HF)

The investigators hypothesize that a simple assessment of peripheral venous pressure (PVP) will better predict the diuretic need and long-term outcomes (all cause mortality, all cause rehospitalization, emergency department visits) compared to standard evaluation.

chronic heart failure
diuretic therapy
heart failure
  • 0 views
  • 23 Mar, 2022
  • 2 locations
18F-DOPA II - PET Imaging Optimization

A single centre non-randomized, non-blinded phase III prospective cohort study of 18F-DOPA PET/CT imaging in specific patient populations: Pediatric patients (less than 18 years old) with congenital hyperinsulinism. Pediatric patients (less than 18 years old) with neuroblastoma. Pediatric (less than 18 years old) or Adult patients (18 or older) with …

parkinson's disease
dementia
dopa
  • 8 views
  • 03 May, 2022
  • 1 location
Dopamine Effect on Inhibitory Control (DEI)

The effect of Levodopa medication on inhibitory control in Parkinson's patients is extremely debated despite the fact that this has potential clinical and therapeutic implications. A key confounding factor of many previous studies is that they did not take the disease duration in consideration. In fact, in moderate-to-advanced stages of …

Accepts healthy volunteers
dopamine agonists
dopa
dyskinesia
levodopa
  • 0 views
  • 02 Jun, 2022
  • 1 location
Dopamine Agonist Treatment of Non-functioning Pituitary Adenomas

-producing adenomas, there is no established pharmacological treatment for NFPAs. However, there are a few non-randomized studies suggesting that treatment with dopamine agonists may slow growth, and also

pituitary disorders
prolactin
pituitary adenoma
non-functioning pituitary adenoma
dopamine agonists
  • 65 views
  • 12 Sep, 2021
  • 3 locations
Effects of Ghrelin Administration on Dopamine and Effort

ghrelin, leptin, and insulin. In addition, the investigators will conduct a set of tasks that have been associated with dopamine function (i.e., effort and reinforcement learning). Second, the

Accepts healthy volunteers
  • 0 views
  • 23 Apr, 2022
Dopamine Action on Metabolism in Relation to Genotype

mass and obesity associated gene (FTO) locus have the highest effect size on body weight. Animal and first clinical studies indicate that FTO variants interact with dopamine signaling in the brain

body mass index
fats
  • 243 views
  • 17 Jun, 2022
  • 4 locations
PSA Versus STN DBS for Dopamine-resistant TD-PD (PSA-STN)

The aim of this study is to compare the effectiveness of the deep brain stimulation in the posterior subthalamic area (PSA) versus the subthalamic nucleus (STN) for the treatment of dopamine

tremor
dopamine
levodopa
brain stimulation
  • 0 views
  • 04 Jul, 2022
  • 1 location
Dopaminergic Mechanisms Underlying Human Social Behavior

Developing theoretical, quantitative models of the basic cognitive mechanisms underlying human social decision-making, and understanding the influence of neuromodulators such as dopamine on

Accepts healthy volunteers
  • 5 views
  • 21 Mar, 2022
  • 1 location
Add-on MEmaNtine to Dopamine Antagonism to Improve Negative Symptoms at First Psychosis

Antipsychotics affects the brain's dopamine system, and the drugs reduce delusions, hallucinations, and disorganized thinking, which are cardinal symptoms of psychotic disorders. However

psychiatric disorder
delusional disorder
amisulpride
hallucinations
schizophrenia
  • 0 views
  • 05 Sep, 2021
  • 1 location
Management of Shock in Children With SAM and Diarrhea

Diarrhea is one of the leading causes of under-five childhood mortality and accounts for 8% of 5.4 million global under-5 deaths. The coexistence of sepsis and hypovolemic shock in children with severe acute malnutrition (SAM) having diarrhea is common. At Dhaka hospital of icddr,b, the death rate is as high …

dopamine
  • 0 views
  • 07 Apr, 2022
  • 1 location