Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 168 clinical trials
Featured trial
A Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose, Parallel-Group Study to Compare the Efficacy, Tolerability, and Safety of 3 Doses of Gabapentin Enacarbil (GSK1838262) With Placebo in the Treatment of Subjects With Moderate-to-Severe Primary Restless Legs Syndrome (RLS)

A Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose, Parallel-Group Study to Compare the Efficacy, Tolerability, and Safety of 3 Doses of Gabapentin Enacarbil (GSK1838262) With Placebo in the Treatment of Subjects With Moderate-to-Severe Primary Restless Legs Syndrome (RLS)

  • 629 views
  • 08 Nov, 2020
  • 1 location
Dopamine Receptor Contributions to Prediction Error and Reversal Learning in Anorexia Nervosa

suggested altered reward processing in AN. The neurotransmitter dopamine has a central role in the reward circuitry to drive food approach, and the dynamic interplay between dopamine receptor response and

  • 29 views
  • 12 Sep, 2021
  • 1 location
The Effect of Dopamine on Pulmonary Diffusion and Capillary Blood Volume During Exercise

The purpose of this study is to examine the effect of dopamine infusion and dopamine-2 receptor blockade on pulmonary capillary blood volume, diffusion, and the hemodynamic variables of

Accepts healthy volunteers
  • 35 views
  • 26 Apr, 2022
  • 1 location
A Translational and Neurocomputational Evaluation of a Dopamine Receptor 1 Partial Agonist for Schizophrenia

This study will test whether CVL-562 (PF-06412562), a dopamine 1 partial agonist novel compound, affects working memory neural circuits in patients with early episode schizophrenia. The overall

  • 24 views
  • 25 Jul, 2022
  • 4 locations
The Role of Dopamine, Reward Learning and Prefrontal Activity in Expectation-induced Mood Enhancement (CRC289A07)

studies show reduced reward processing in clinical and subclinical depression, presumably due to abnormalities in the dopamine (DA) system. Here, the investigators will test whether expectation-induced

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
Contribution of L-Tyrosine to Human Decision Making in Stressful Situations (TYRO-STRESS)

L-tyrosine is a chemical precursor of dopamine. Under specific conditions, tyrosine administration can increase brain dopamine levels and therefore several studies have explored whether tyrosine

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
[C-11]NPA PET-amphetamine in Cocaine Use Disorders

This study uses [11C]NPA positron emission tomography (PET) and a d-amphetamine challenge to image amphetamine induced dopamine release in the striatum in subjects with cocaine use disorders

  • 0 views
  • 08 Jul, 2022
  • 1 location
Exercise in Methamphetamine Use Disorder Upregulation and Neural Function

The purpose of this research study is to determine the effects of an exercise intervention and health-education program on brain dopamine receptors and on cognitive functions that have been

  • 20 views
  • 25 May, 2022
  • 1 location
Does Caffeine Facilitate Human Reward Learning Behaviors? (ADoRe)

affecting the brain and nervous system. By such effects, caffeine enhances reward signals - dopamine - in human brains. In this research study, we will find out whether taking caffeine acutely or daily can

Accepts healthy volunteers
  • 0 views
  • 03 Jun, 2022
  • 1 location
Developing an EEG Paradigm to Study Prediction Error in Anorexia Nervosa

altered reward processing in AN including in studies using the dopamine associated prediction error (PE) model. The brain PE response is elicited during unexpected receipt or omission of reward stimuli

Accepts healthy volunteers
  • 0 views
  • 20 Apr, 2022
  • 1 location