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Found 27 clinical trials
Effect of Hydralazine on Alzheimer's Disease (EHSAN)

one of the acetylcholinesterase inhibitor (AChEI) donepezil, rivastigmine, or galantamine.

mini-mental state examination
rivastigmine
acetylcholinesterase inhibitor
stroke
galantamine
  • 0 views
  • 21 Mar, 2022
  • 1 location
Improving Sleep and Cognition in Alzheimer's Disease

treatment with donepezil.

cognitive impairment
cognitive assessment
cognitive decline
donepezil
mild cognitive impairment
  • 0 views
  • 17 Jun, 2022
  • 2 locations
tDCS on Parkinson's Disease Cognition (tDCS-PD-fMRI)

dysfunction is one of the most significant factors affecting the quality of life of patients with PD. While dementia in Parkinson's disease is routinely treated by cholinesterase inhibitors (e.g., donepezil

demented
parkinsonism
rivastigmine
dementia
motor symptoms
  • 168 views
  • 20 Apr, 2022
  • 1 location
ALDH Enzyme in CRF With Advanced GI Cancer (ALDHCRF)

Aldehyde dehydrogenase (ALDH) enzyme supplementation plays an essential role in the elimination of toxic metabolites and reduction of reactive oxygen species bioactivation, which can protect and relieve chemotherapy-related fatigue (CRF) in cancer patients. The aim of this study is to evaluate the efficacy and safety of ALDH enzyme in CRF …

cancer
  • 0 views
  • 25 Mar, 2022
  • 1 location
Noradrenergic Add-on Therapy With Guanfacine (NorAD)

NorAD is a clinical trial funded by the UK National Institute of Health Research. In this trial the investigators will assess whether a long-acting preparation of guanfacine, a drug used to treat Attention Deficit Hyperactivity Disorder in children, can improve thinking (particularly attention) in Alzheimer's Disease when it is added …

mini-mental state examination
cognitive assessment
donepezil
galantamine
rivastigmine
  • 9 views
  • 05 Jul, 2022
  • 1 location
A Pilot Study of Creatine Monohydrate as an Augmenting Agent for ECT in Persons With Major Depressive Disorder

We propose to determine if augmentation of electroconvulsive therapy (ECT) utilized for the treatment of major depressive disorder (MDD) with daily oral creatine will lead to an accelerated response to treatment, an overall increase in response rate, and will protect against cognitive adverse effects associated with ECT. We propose to …

creatine monohydrate
major depressive disorder
electroconvulsive therapy
depression
  • 0 views
  • 05 Jun, 2022
  • 1 location
Visualising Cerebral and Peripheral Cholinergic Nerves in Patients With Dementia Lewy Bodies.

Lewy Body Dementia (DLB) is the second most common type of neurodegenerative dementia and characterized by loss of cholinergic neurons in the cerebrum and possibly also internal organs. A novel tracer, 18F-fluoroethoxybenzovesamicol (18F-FEOBV), binds to the cholinergic vesicle transporter, a protein expressed uniquely in the vesicles of cholinergic pre-synapses. Our …

PET-CT
fdg-pet
dopamine
dementia
behavioral disorder
  • 0 views
  • 03 Jun, 2022
  • 1 location