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Found 27 clinical trials
Efficacy and Safety of ChOline ALfoscerate in Patient With Mild to Moderate Alzheimer's Disease (COALA)

The purpose of this study is to determine whether combination of donepezil, a cholinesterase inhibitor, with choline alfoscerate has a more favourable clinical profile than monotherapy with

donepezil
alzheimer's disease
cholinesterase
  • 0 views
  • 08 Jun, 2022
  • 3 locations
The Effect of Donepezil in Radiotherapy-related Cognitive Impairment.

Purpose: This randomized, double-blind, placebo-controlled clinical trial aims to evaluate the therapeutic effects of donepezil in radiotherapy-related cognitive impairment. Further study

donepezil
mini-mental state examination
cancer
  • 0 views
  • 19 Feb, 2022
  • 1 location
Donepezil and Cognitive Training for Alcohol Use Disorder (AUD)

The goal of the project is to evaluate whether donepezil + cognitive remediation therapy is superior to placebo in reducing heavy drinking in patients with alcohol use disorder in a double-blind

  • 0 views
  • 10 May, 2022
  • 1 location
Efficiency of Donepezil in Elderly Patients for Prevention of POCD Dysfunction

method was proved. According to our previous study, the central cholinergic system impaired by the anesthesia and surgery play a very important role in the POCD and donepezil an acetylcholinesterase

total knee replacement
anesthesia
  • 0 views
  • 28 Jan, 2021
  • 1 location
The Effect of Donepezil on Glycemic Control in Type II Diabetics

The purpose of the study is to establish the effectiveness of the drug Donepezil in treating Type 2 Diabetes Mellitus compared to a control treatment. Donepezil is not approved by the FDA to

hypertension
  • 0 views
  • 28 Oct, 2021
  • 1 location
Donepezil for Oxaliplatin-induced Neuropathy Peripheral Neuropathy: Proof of Concept Study (DONEPEZOX)

, no treatment remains univocal for these peripheral neuropathies. But preclinical works have demonstrated that donepezil (acetylcholinesterase inhibitor use for Alzheimer's disease) was able to

  • 0 views
  • 28 Jun, 2022
  • 22 locations
Evaluation of the Contribution of Regular Cognitive Exercises to Treatment in Patients With Alzheimer's Disease

In this study, it is aimed to compare the effects of cognitive exercises applied on long-term internet environment to the cognitive level of patients who received donepezil, memantine or

donepezil
memantine
alzheimer's disease
dementia
  • 0 views
  • 24 May, 2022
  • 1 location
Cognition Platform Study in Participants at Risk for Alzheimer's Disease (AD) (MK-0000-413)

The main purpose of this study is to assess the ability of a repeated high-frequency site-based computerized cognitive assessment to evaluate the potential treatment effects of donepezil (MK

donepezil
apolipoprotein e
cognitive assessment
cognitive impairment
mild cognitive impairment
  • 14 views
  • 20 Jun, 2022
  • 8 locations
The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's (LUCINDA)

taking a stable dose of donepezil (Aricept.) Its objective is to assess the efficacy of a 48-week regimen of leuprolide (22.5 mg per 12 weeks) compared to placebo on cognitive function, global function

donepezil
memantine
aricept
cognitive impairment
dementia
  • 47 views
  • 28 Feb, 2022
  • 1 location
Transmagnetic Stimulation Pilot in Early Stage Alzheimer's Disease

tangles. Available FDA-approved medications for AD such as donepezil and memantine offer limited benefit and modest impact on quality of life. In combination with resting state functional MRI (rs-fMRI

donepezil
memantine
amyloidosis
cholinesterase inhibitors
cognitive impairment
  • 0 views
  • 22 Apr, 2022
  • 1 location