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Found 298 clinical trials
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A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression On or After Platinum-Based Chemotherapy and Checkpoint Inhibitor Therapy (SAPPHIRE)

docetaxel in patients with advanced non-squamous NSCLC who have previously experienced radiographic disease progression on or after treatment with platinum-based chemotherapy in combination with CIT.

platinum-based chemotherapy
advanced non-squamous non-small cell lung cancer
nivolumab
cancer chemotherapy
lung cancer
  • 199 views
  • 24 May, 2021
  • 175 locations
featured
RTOG 1216: Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered With Concurrent Cisplatin Versus Docetaxel Versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer of the Head and Neck

RTOG 1216: Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered With Concurrent Cisplatin Versus Docetaxel Versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer

  • 470 views
  • 08 Nov, 2020
  • 1 location
featured
Phase 3 Study of MRTX849 vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-12)

This Phase 3 study will evaluate the efficacy of the investigational agent MRTX849 versus docetaxel in patients who have been previously treated for metastatic NSCLC with a KRAS G12C mutation.

refractory non-small cell lung cancer
advanced lung cancer
recurrent non-small cell lung cancer
metastatic non-small cell lung cancer
lung cancer
  • 0 views
  • 08 Jun, 2021
  • 34 locations
featured
  • 228 views
  • 08 Nov, 2020
  • 1 location
featured
Spectrum Neutropenia in Breast Cancer

Spectrum Neutropenia in Breast Cancer

  • 76 views
  • 08 Nov, 2020
  • 1 location
featured
Prostate Cancer

Prostate Cancer

  • 72 views
  • 08 Nov, 2020
  • 1 location
featured
A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Screening Step) Lung-MAP Study

A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Screening Step) Lung-MAP Study

lung cancer
cancer
lung carcinoma
  • 28 views
  • 23 Nov, 2020
  • 1 location
Docetaxel Compared With Observation in Treating Patients Who Have Undergone Radical Prostatectomy for Prostate Cancer

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving

immunological adjuvant
prostatectomy
tumor cells
docetaxel
  • 35 views
  • 07 Nov, 2020
  • 5 locations
Evaluation of Maxy-G34 in Breast Cancer Patients Treated With TAC (Docetaxel Adriamycin Cyclophosphamide) Chemotherapy

This is an investigation of the safety and efficacy of Maxy-G34 in breast cancer patients treated with TAC chemotherapy. Maxy-G34 will be given as a single injection during each cycle of chemotherapy, for a planned total of six chemotherapy cycles.

adriamycin
docetaxel
immunostimulant
cyclophosphamide
anthracyclines
  • 68 views
  • 07 Nov, 2020
  • 1 location
Pembrolizumab/Vibostolimab Coformulation (MK-7684A) or Pembrolizumab/Vibostolimab Coformulation Plus Docetaxel Versus Docetaxel for Metastatic Non Small Cell Lung Cancer (NSCLC) With Progressive Disease After Platinum Doublet Chemotherapy and Immunotherapy (MK-7684A-002)

The main purpose of this study is to compare pembrolizumab/vibostolimab coformulation (MK-7684A) plus docetaxel or pembrolizumab/vibostolimab coformulation to normal saline placebo plus

  • 0 views
  • 23 Jun, 2021
  • 20 locations