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Found 73 clinical trials
Featured trial
Are you undergoing treatment for Congestive Heart Failure?

Are you undergoing treatment for Congestive Heart Failure?

  • 08 Nov, 2020
  • 1 location
Featured trial
Patients with Heart Failure and currently on a loop diuretic

The purpose of this study is to evaluate the action of the study drug on your kidneys and your ability to eliminate salt and water alongside a diuretic (furosemide). The information gathered during this clinical trial may support further drug development, including larger trials in patients with heart failure.  The study …

heart failure
  • 23 Nov, 2020
  • 1 location
Impact of Hypertonic Saline Solution on Acute Decompensated Heart Failure (HSS)

Acute decompensated heart failure (HF) is one of the most common cardiologic issues in emergency departments. Loop diuretics have long been recognized as the key for the treatment of

  • 18 Apr, 2022
  • 1 location
A Pivotal Phase 3 Randomized, Placebo-controlled Clinical Study to Evaluate the Efficacy and Safety of the sGC Stimulator Vericiguat/MK-1242 in Adults With Chronic Heart Failure With Reduced Ejection Fraction (VICTOR)

symptomatic chronic HFrEF who have not had a recent hospitalization for heart failure or need for outpatient intravenous (IV) diuretics. The primary hypothesis is that vericiguat is superior to placebo in

  • 29 Oct, 2022
  • 389 locations
Insulin Dextrose Infusion vs Nebulized Salbutamol vs Combination of Salbutamol and Insulin Dextrose in Acute Hyperkalemia (InSaKa)

Hyperkalemia is a common electrolyte disorder, especially among patients with chronic kidney disease, diabetes mellitus, or heart failure. Globally, the reported incidence of hyperkalemia varies from 1.1 to 10 per 100 hospitalizations, depending on the patient cohort and comorbidities. Hyperkalemia is a potentially life-threatening electrolyte disturbance that can be fatal …

  • 26 Mar, 2022
  • 4 locations
Digoxin Short Term Treatment Assessment Randomized Trial in AHF (DIG-STA-AHF)

AHFS management is challenging and most of the used drugs has failed to decrease post-discharge mortality and readmission rates which represent the most important goal in AHFS. Digoxin processes many characteristics of a beneficial drug for heart failure, however recent publications has rose concerns about its safety profile and therefore …

  • 08 Jul, 2022
  • 2 locations
Patient SELF-management With HemodynamIc Monitoring: Virtual Heart Failure Clinic and Outcomes (the SELFIe-HF Trial): Program (SELFIe-HF)

complications and is cost-effective, in New York Heart Association (NYHA) class III and II (requiring diuretics) patients.

  • 27 Oct, 2022
  • 1 location
Minimally Invasive Vestibular Neurectomy Versus Tenotomy of the Stapedius and Tensor Tympani Muscles in the Management of Patients With Unilateral Meniere's Disease

modifications, such as low-sodium diet, avoidance of caffeine, alcohol and stress, in addition to medication such as diuretics and betahistine. When conservative treatment fails, surgical management is

  • 18 Jul, 2021
  • 1 location
Ventilation Tube Insertion for Unilateral Meni re's Disease

The purpose of this trial is to assess the effects of transmyringeal ventilation tubes compared with sham-treatment which do not ventilate the middle ear, on the number of vertigo attacks lasting more than 20 minutes in participants with Menire's disease.

  • 20 Oct, 2021
  • 1 location
Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement - a Randomized Controlled Trial (STARC)

Statins have rapid and significant actions that have potentially important (but not yet proven) implications for postoperative atrial fibrillation and cardiac protection in patients undergoing cardiac surgery. The focus of this study is, therefore, on patients having surgical aortic valve replacement (with aortotomy) and the development of postoperative atrial fibrillation …

  • 22 Oct, 2022
  • 1 location