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Found 12 clinical trials
Prevention of Mortality With Long-Term Administration of Human Albumin in Subjects With Decompensated Cirrhosis and Ascites (PRECIOSA)

with ascites (or with prior history of ascites requiring diuretic therapy) with or without acute-on-chronic liver failure (ACLF) at admission or during hospitalization but without ACLF at discharge.

  • 35 views
  • 17 Sep, 2022
  • 30 locations
Effect of Dapagliflozin in Patients With Acute Heart Failure (DAPA-RESPONSE-AHF)

renin angiotensin- aldosterone activity. Thus, adding SGLT2i to the standard loop diuretic therapy might confer additional decongestive and natriuretic benefits while avoiding the adverse electrolyte

  • 0 views
  • 19 Jun, 2022
  • 1 location
Evaluation of Blood Volume Analysis- Guided Management of Decompensated Heart Failure

Diuretic therapy is first-line treatment for acute decompensated heart failure. However, accurate assessment and management of patient blood volume is challenged by the limitations of physical

  • 0 views
  • 04 Oct, 2022
  • 1 location
PVP-Guided Decongestive Therapy in HF (PERIPHERAL-HF)

The investigators hypothesize that a simple assessment of peripheral venous pressure (PVP) will better predict the diuretic need and long-term outcomes (all cause mortality, all cause rehospitalization, emergency department visits) compared to standard evaluation.

diuretic therapy
chronic heart failure
heart failure
  • 0 views
  • 23 Mar, 2022
  • 2 locations
Protocolized Diuretic Therapy Compared to Standard Care in Emergency Department Patients With Acute Heart Failure

This is a randomized trial of protocolized diuretic therapy guided by urinary sodium compared to structured usual care in ED patients with AHF. Participants will be recruited following an

acute heart failure
diuretic therapy
edema
heart failure
  • 0 views
  • 04 Jun, 2022
  • 1 location
Efficacy and Safety of Dapagliflozin in Acute Heart Failure (DICTATE-AHF)

following an initial standard evaluation in the ED and randomized within 24 hours of presentation for ADHF in a 1:1 fashion to protocolized diuretic therapy or dapagliflozin + protocolized diuretic therapy

orthopnea
decompensated heart failure
heart failure
dyspnea
diuretics
  • 58 views
  • 21 Mar, 2022
  • 6 locations
Diuretic Treatment in Acute Heart Failure With Volume Overload Guided by Serial Spot Urine Sodium Assessment (DECONGEST)

) on spot urine samples after diuretic administration and with low-threshold use of combination diuretic therapy, improves decongestion versus usual care in acute heart failure (AHF), potentially

  • 0 views
  • 03 Jul, 2022
  • 1 location
Ertugliflozin in Chronic Heart Failure

use in acute settings and chronic oral loop diuretic therapy. There are two general purposes for this study. The proposed study is both larger and more rigorous than essentially all PK/PD

furosemide
heart failure
loop diuretic
diuretic therapy
chronic heart failure
  • 0 views
  • 24 May, 2022
  • 1 location
Efficacy and Safety of Early Initiation of Canagliflozin in Patients With Acute Decompensated Heart Failure

The study aims to investigate the efficacy and safety of the early initiation of canagliflozin treatment in hospitalized heart failure patients with volume overload (warm-wet) who require the use of I.V loop diuretic during the hospitalization period.

glomerular filtration rate
  • 0 views
  • 20 Sep, 2022
  • 1 location
VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit (AKIVEX)

A quasi experimental study that aims to verify whether the incorporation of VExUS in patients with AKI in the Intensive Care Unit (ICU) may prompt tailored interventions to increases the number of days free from Renal Replacement Therapy (RRT) during the first 28 days.

renal replacement therapy
  • 0 views
  • 22 Mar, 2022
  • 1 location