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Found 1941 clinical trials
Long-term Outcome of General Anesthesia on Dysgnosia

Cognitive disorders in patients underwent general anesthesia are discussed for decades, but whether there were precise relationship between general anesthesia and dysgnosia is yet to be guaranteed. Although controversial data reported from experimental studies in animals, the investigators still proposed that general anesthetics could impair the normally organized system of …

intravenous anesthetics
  • 08 Nov, 2020
  • 1 location
TIME ASPIRIN: Chronotherapy With Aspirin for Reduction of Cardiovascular Disease

This study will be a comparative effectiveness research to determine the difference in major adverse cardiovascular events between the group with aspirin after awakening and placebo before bedtime and the group with placebo after awakening and aspirin before bedtime.

  • 23 Jan, 2021
  • 1 location
Genetic Testing to Understand and Address Renal Disease Disparities Across the United States

The primary aim is to determine the effect of participant and provider knowledge of a positive APOL1 status and accompanying guideline based clinical decision support (CDS) on blood pressure management on change in systolic blood pressure (SBP) from baseline to 3 months after randomization among the APOL1 positive participants. Secondary …

apolipoprotein l1
antihypertensive drugs
hemoglobin a1c
  • 07 Mar, 2021
  • 9 locations
Yorkshire Enhanced Stop Smoking Study

Lung cancer rates are higher in Yorkshire than the rest of the UK, and this is due to higher rates of smoking. Deaths from lung cancer can be reduced using regular lung scans (screening) and by helping people stop smoking. As well as detecting cancers, scans can also show evidence …

smoking cessation
myocardial infarction
lung cancer
  • 25 Jan, 2021
  • 1 location
Expanding Live Donor Kidney Transplantation Through Advocacy Training and Social Media

This pilot study will be a clinical trial to test the feasibility and effectiveness of an educational intervention and a mobile health intervention in adults with end stage renal disease (ESRD) who have not yet identified a potential live donor.

renal failure
kidney transplant
chronic renal failure
  • 26 Jan, 2021
  • 2 locations
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions

This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic conditions. Clinically observed initial findings and an extensive body of research indicate regenerative treatments are both safe and effective for the treatment of multiple conditions.

  • 28 Jan, 2021
  • 1 location
Evaluating Innovations in Transition From Pediatric to Adult Care - The Transition Navigator Trial

The Transition Navigator Trial (TNT) is a pragmatic randomized controlled trial evaluating the effectiveness of usual care plus a patient navigator service versus usual care plus newsletters and other educational materials, to improve transition outcomes among adolescents aged 16-21 who have chronic health conditions requiring transfer to adult specialty care. …

  • 02 May, 2021
  • 3 locations
Correcting Myopia Among Secondary School Children to Increase Academic High School Attendance Rates in Rural Communities

Chinese children are some of the most short-sighted in the world, but only one in five children in poor areas who needs glasses has them. Our team has already shown in other trials that giving children free glasses leads to better grades and that free glasses have a bigger impact …

a 10
  • 23 Jan, 2021
  • 2 locations
Dupilumab in CRSsNP

Primary Objective: Part A and B: To evaluate the efficacy of dupilumab as assessed by the reduction at Week 24 in sinus opacification on CT scan and sinus total symptom score (sTSS) compared to placebo Secondary Objectives: Part A To evaluate the efficacy of dupilumab as assessed by the reduction …

  • 23 Apr, 2021
  • 14 locations
Function Integrity of Neck Anatomy in Thyroid Surgery

Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might …

  • 26 Jan, 2021
  • 1 location