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Found 35 clinical trials
Clinical Trial for Near Infrared Endoventricular Illumination for Neuroprotection in Very Early Cases of Parkinson's Disease (Ev-NIRT) (Ev-NIRT)

Parkinson's disease has only pharmacological (essentially dopaminergic) and surgical treatment (essentially high-frequency deep brain stimulation), that are symptomatically effective. none of them is curative, and has the ability to slow down the disease and to protect dopaminergic neurons from death by neurodegeneration. Experimental results, based on preclinical studies, suggest that …

  • 0 views
  • 25 May, 2022
  • 1 location
Video-oculography and Parkinson's Disease

This study aims to study, in patient with Parkinson's disease, mild to moderate stage (according to Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's Disease, Postuma et al., 2015): the evolution of oculomotricity markers over time. the correlation between neurological evaluations (motor and non-motor scores), neuropsychological evaluations (cognitive disorders) and …

dopa
ct scan
datscan
movement disorder
antiparkinsonian agents
  • 0 views
  • 25 Jan, 2022
  • 1 location
TAME-PD - Physical Therapy, Atomoxetine and, Methylphenidate, to Enhance Gait and Balance in Parkinson's Disease (TAME-PD)

Gait and balance problems are a significant source of disability in patients with Parkinson disease. Physical therapy remains one of the main treatments. On the other hand some medications, such as methyphenidate and atomoxetine, have been tried with promising results. The outcomes in gait and balance in Parkinson disease after …

medication regimen
  • 18 views
  • 23 Mar, 2022
  • 1 location
Cam Decompression Utilizing the Stryker Hip-Check Software Platform

Accurate femoroplasty has been shown to be critical in achieving success following treatment of femoroacetabular impingement (Matsuda, Schnieder, and Sehgal 2014; Mansor et al. 2018; Larson et al. 2014). Nearly 75% of cases undergoing revision hip arthroscopy do so due to residual femoroacetabular impingement (Ricciardi et al. 2014). Femoroplasty remains …

  • 22 views
  • 28 Aug, 2021
  • 1 location
Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

The purpose of this study is to determine whether a lung transplantation prior to bone marrow transplantation (BMT) would allow for restoration of pulmonary function prior to BMT, allowing to proceed to BMT, to restore hematologic function.

a hemoglobin
COPD
immunosuppressant
pulmonary disease
emphysema
  • 115 views
  • 26 Mar, 2022
  • 2 locations
Dose Dense Rituximab for High Risk Newly Diagnosed Acute Immune Thrombocytopenic Purpura

The purpose of this study is to determine if a dose dense administration of Rituximab in newly diagnosed acute immune thrombocytopenic purpura (ITP) and determine relapse rate following this treatment. Correlative studies will be performed as outlined in the appendices. Quality of Life will be measured using the KIT as …

platelet count
eltrombopag
kidney function tests
romiplostim
rituximab
  • 0 views
  • 14 Aug, 2021
  • 1 location
Arrhythmogenic Substrate in Primary Cardiomyopathies and/or Channellopathies

This study assesses the value of arrhythmogenic substrate identification and elimination by catheter ablation to prevent recurrent ventricular arrhythmias and sudden cardiac death in a series of selected patients with primary cardiomyopathy and/or channellopaties with ICD implantation.

sudden cardiac death
cardiomyopathy
arrhythmia
idiopathic cardiomyopathy
fibrillation
  • 21 views
  • 08 May, 2021
  • 1 location
FAPI PET for Lung Fibrosis (FAPI ILD)

This is a prospective exploratory biodistribution study in patients with interstitial lung disease (ILD). The purpose of this research study is to determine where and to which degree the FAPI tracer (68Ga-FAPI-46) accumulates in normal and fibrotic lung tissues of patients with interstitial lung disease. The study will include patients …

covid-19
interstitial lung disease
ct scan
lung biopsy
pulmonary fibrosis
  • 0 views
  • 30 May, 2022
  • 1 location
Palliative Care Planner (PCplanner)

The purpose of this research study is to determine the feasibility, acceptability, and evidence for clinical impact of a mobile app-based program called Palliative Care Planner (PCplanner) in addressing needs and promoting advance care planning discussions among patients with idiopathic pulmonary fibrosis and their clinicians.

interstitial lung disease
idiopathic pulmonary fibrosis
fibrosis
pulmonary fibrosis
  • 0 views
  • 22 Apr, 2022
  • 1 location
A Multicenter Randomized Open-label Study of Diammonium Glycyrrhizinate Enteric-coated Capsule Plus DXM Versus DXM in Treatment of ITP

The project was undertaking by Qilu Hospital of Shandong University in China. In order to report the efficacy and safety of diammonium glycyrrhizinate enteric-coated capsule plus high-dose dexamethasone for the treatment of adults with newly-diagnosed primary immune thrombocytopenia (ITP).

thrombocytopenia
platelet count
dexamethasone
  • 2 views
  • 03 Sep, 2021
  • 2 locations