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Found 894 clinical trials
Eye-Control Trial: Wearable Eye-Tracking Device as Means of Communication

The purpose of this study is to evaluate the feasibility of use of a wearable communication device for critically ill patients who are admitted to the intensive care unit (ICU) and mechanically ventilated. The study will assess the safety, tolerability, and ease of use of the EyeControl device, and examine …

  • 4 views
  • 03 May, 2022
  • 1 location
Sitting Position and Blood Oxygenation in ICU Patient

The positioning of the ICU patient is a daily concern of the medical and paramedical teams. Developments in emergency medicine and sedation and analgesia techniques have made it possible to reduce patient mortality. However, considered too unstable, patients were no longer mobilized outside the bed until the complete resolution of …

  • 4 views
  • 09 Jul, 2021
  • 1 location
The Clinical Impact of L-PRF H-PRF or the Use of Surgical Stent on Palatal Donor Site Healing.

A Randomized, Three Parallel Arms Clinical Trial to evaluate s the clinical impact of L-PRF vs H-PRF vs Palatal stent on the healing of the donor palatal site.

  • 0 views
  • 11 Mar, 2021
  • 1 location
Use of Repris Needle in Bladder Injection

Treatment of overactive bladder (OAB) has been treated successfully by the injection of Botox. The Repris injection needle has a deflection that may assist in injection difficult to reach with standard straight needles. This study will assess the success, safety and patient tolerance of this new injection needle.

  • 9 views
  • 05 Aug, 2021
  • 1 location
Post-operative Urinary Retention (POUR) Following Thoracic Surgery (POUR)

Inability to urinate a common complication that happens to many patients after a surgery, especially in men over 60 years of age who undergo surgery on their chest. Urinary retention is uncomfortable, increases anxiety, increases hospital length of stay, and leads to more procedures such as putting in a bladder …

Accepts healthy volunteers
  • 9 views
  • 12 Feb, 2022
  • 1 location
Effectiveness of a Web-based Intervention on Parental Psychological Flexibility and Emotion Regulation

This project aims to validate a web-based clinical intervention for families with children suffering neurodevelopmental or behavioral disorders to promote psychological flexibility and emotion regulation strategies in parents.

Accepts healthy volunteers
  • 0 views
  • 26 Feb, 2022
  • 2 locations
Safety and Efficacy Trial of AAV Gene Therapy in Patients With CNGB3 Achromatopsia

This will be a non-randomized, open-label, Phase 1/2 study of the safety and efficacy of AGTC-401 administered to one eye by subretinal injection in individuals with achromatopsia caused by mutations in the CNGB3 gene. The primary study endpoint will be safety and the secondary study endpoint will be efficacy.

  • 0 views
  • 26 Jan, 2022
  • 8 locations
Safety and Efficacy Trial of AAV Gene Therapy in Patients With CNGA3 Achromatopsia

This will be a non-randomized, open-label, Phase 1/2 study of the safety and efficacy of AGTC-402, administered to one eye by subretinal injection in individuals with achromatopsia caused by mutations in the CNGA3 gene. The primary study endpoint will be safety and the secondary study endpoint will be efficacy.

  • 153 views
  • 27 Jan, 2022
  • 8 locations
Proton Versus Photon Therapy in Anal Squamous Cell Carcinoma

Dosimetric studies suggest that radiotherapy with protons has a potential to reduce side effects compared to treatment with photons for patients with anal carcinoma (AC). There are so far no studies comparing these treatment techniques in a randomised setting. The aim of this study is to compare side effects following …

  • 0 views
  • 10 Oct, 2021
  • 1 location
Topical Timolol: a Comparison of Surgical Outcomes

The use of topical beta-blockers, such as 0.25% timolol, in promoting wound healing is currently emerging in the literature. The investigators will enroll 30 participants in a split scar study who have their skin cancer surgically removed resulting in a linear wound equal to or longer than 4cm. The objective …

Accepts healthy volunteers
  • 0 views
  • 18 Nov, 2021
  • 1 location