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Found 18 clinical trials
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Pragmatic Randomized Controlled Trial of Non-pharmacological Treatment for Lumbar Disc Herniation : A Pilot Study

This is a 2-arm parallel pragmatic randomized controlled trial that will compare non-pharmacological treatment with pharmacological therapy for lumbar disc herniation.

  • 0 views
  • 09 Aug, 2021
  • 1 location
None
Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy

The purpose of this study is to determine a grading system for inflammation in lumbar disc herniation and which groups, if any, benefit most from the administration of an intra-operative epidural steroid.

radiculopathy
dexamethasone
conservative management
discectomy
  • 11 views
  • 26 Jan, 2021
  • 2 locations
None
SI-6603 (Condoliase) Study for Lumbar Disc Herniation (Discovery 6603 Study)

This study is to evaluate the effectiveness of a single-dose intervertebral disc injection of SI-6603 in subjects with lumbar disc herniation (LDH)

condoliase
radiculopathy
leg pain
  • 1788 views
  • 10 Oct, 2021
  • 95 locations
None
Repairing the Defect of Intervertebral Disc With Autologous BMSC and Gelatin Sponge After Microendoscopic Discectomy for Lumbar Disc Herniation

In this prospective study the investigators seek to evaluate clinical outcomes after repairing the defect of intervertebral disc with autologous BMSC/gelatin sponge during microendoscopic discectomy for participants of lumbar disc herniation.

conservative management
discectomy
  • 318 views
  • 29 Oct, 2021
  • 2 locations
None
Efficacy and Safety of IntraSPINE Associated With Discectomy in the Treatment of Lumbar Disc Herniation.

IntraSPINE is a novel device that, unlike interspinous positioned implants, is unique in being placed more anteriorly in an interlaminar position, closer to the normal center of rotation of the motion segment. Mechanical advantages are thus conferred over more posteriorly positioned devices through the possibility of more physiological 'rocking' type …

discectomy
  • 44 views
  • 25 Jan, 2021
  • 1 location
None
Human Umbilical Cord Mesenchymal Stem Cells For the Treatment of Lumbar Disc Degeneration Disease

This study aims to investigate the safety and efficiency of Human Umbilical Cord Mesenchymal Stem Cells (hUCMSC) for treating lumbar disc degeneration diseases. We hypothesize grafting hUCMSC into the degenerative disc leads to symptoms relief and slow down the progression of disc degeneration.

back pain
radicular pain
discectomy
morphine
conservative management
  • 0 views
  • 24 Jan, 2021
None
Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion

This study will describe postoperative pain management for spine surgery patients receiving liposomal bupivacaine (Exparel) compared to patients not receiving the drug.

stenosis
exparel
spine surgery
disc disease
spinal fusion
  • 12 views
  • 29 Jan, 2021
  • 2 locations
None
Effect of Fibromyalgia on Outcomes of Transforaminal Epidural Steroid Injection Treatment in Lumbar Radicular Pain

Lumbar radicular pain is defined as low back and leg pain caused by inflammation in the affected nerve root due to various etiological factors. In its treatment, there are various options such as anti-inflammatory drugs, physical therapy modalities, exercises, epidural steroid injections, and surgery. Epidural steroid injections have also become …

  • 0 views
  • 01 Oct, 2021
  • 1 location
None
Effect of Metabolic Syndrome on Outcomes of Transforaminal Epidural Steroid Injection Treatment in Chronic Lumbar Radiculopathy

Transforaminal epidural steroid injection (TFESI) has been increasingly preferred in patients who can not benefit from conservative approach in the treatment of lumbosacral radiculopathic pain due to lumbar disc herniation. The aim of our study is to evaluate the effect of metabolic syndrome on the treatment results of transforaminal epidural …

  • 0 views
  • 27 Oct, 2021
  • 1 location
None
Cortical Bone Trajectory Screws vs. Traditional Pedicle Screws Fixation

Transforaminal lumbar interbody fusion (TLIF) had been favorable for effectively decrease pain and disability in specific spinal disorders; however, there has been concern regarding pedicle screw placement during TLIF surgery. Recently, several biomechanical studies had demonstrated that CBT technique achieves screw purchase and strength equivalent to or greater than the …

stenosis
back pain
conservative management
disc disease
  • 1 views
  • 22 Jan, 2021
  • 1 location