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Found 10 clinical trials
Featured trial
C3991004 - Obesity

The purpose of this study is to find out if PF-07081532 ("the active study drug"), is safe and helps treat people with obesity without diabetes to lose weight, and people with diabetes to keep their blood sugar in good control. Individuals diagnosed with diabetes that are on metformin or individuals …

metformin
diabetes
sugars
  • 44 views
  • 30 Jan, 2023
  • 29 locations
Infliximab and Adalimumab in Irritable Bowel Disease Patients.

This study aims to assess trough, TREM-1 levels and efficacy of IFX and ADA in IBD patients.

infliximab
colitis
adalimumab
enteropathy
  • 0 views
  • 12 Apr, 2022
Clinical Study on the Treatment of Pediatric Hemophagocytic Lymphohistiocytosis Based on Cytokine Guided Risk Stratification:A Multicenter Randomized Controlled Study

Hemophagocytic lymphohistiocytosis (HLH) is a rapidly fatal disease caused by immune-dysregulation characterized by hypercytokinemia, with about 30%-40% of patients suffering death in children. Stratification strategy and individualized treatment is important to improve the survival. In our recent retrospective study, risk stratification based on IL-10 and IFN-γ levels well distinguished patients …

  • 0 views
  • 27 Oct, 2022
  • 1 location
Interest of Famotidine in Reducing Endothelial Expression of P-selectin in Children With Sickle Cell Disease: Pilot Study, Single-center, Prospective, Non-comparative. (FAMODREP)

The purpose of this study is to determine whether oral famotidine, a histamine type 2 receptor antagonist already widely used with very few side effects in other indications in children, is effective in reducing endothelial expression of P-selectin in children with sickle cell disease (SCD). This pilot study will constitute …

glutamine
chest syndrome
hydroxyurea
vaso-occlusive crisis
voxelotor
  • 0 views
  • 28 Oct, 2022
  • 1 location
DTG Plus 3TC for Prophylaxis of Mother-to-child Transmission of HIV Infection in Pregnant Women (PREGNANT)

The study aims to evaluate the safety and efficacy of a 2 drugs ART regimen (lamivudine plus dolutegravir) for prevention of mother to child transmission in pregnant women with HIV. 20 pregnant women will be enrolled in this proof of concept protocol. They will be prescribed DTG-3TC (fixed-dose combination), and …

dolutegravir
lamivudine
Accepts healthy volunteers
mother-to-child transmission
  • 0 views
  • 25 Mar, 2022
  • 1 location
Evaluation of (Surgery and Endoscopy) in Management of Indeterminate Common Bile Duct Stricture

Evaluate the lower indeterminate CBD strictures trying to reach possible diagnosis by all available methods i.e brush cytology ,bile aspirate cytology , tissue biopsy ,imaging studies and laboratory work up then treatment of the patient either endoscopically or surgically according to the etiology.

Accepts healthy volunteers
  • 0 views
  • 08 Dec, 2021
  • 1 location
Clinical Efficacy and Safety of Fecal Microbiota Transplantation

Changes in the fecal microbiota are known to be involved in the etiology of several diseases. The purpose of this study is to evaluate the effectiveness and safety of fecal microbiota transplantation (FMT) in diseases known to be associated with intestinal microbial inbalance. .

  • 0 views
  • 04 Jun, 2021
  • 1 location
Evaluation of Outcomes From Treatment of Benign or Malignant Gastroesophageal Diseases

This study will be a retrospective chart review of patients who have been diagnosed with benign or malignant pancreatic disease under the practice of Dr. Rohan Jeyarajah, M.D., Dr. Houssam Osman M.D., and Dr. Edward Cho M.D., Sc.M. at Methodist Health System Hospital in Richardson, TX. The Investigators plan to …

  • 0 views
  • 25 Mar, 2022
  • 1 location
Morbidity Mortality Short and Long-term Survival of Hemodialysis End-stage Kidney Disease Patients in Central Tanzania

Background: In the last 2 decades, Tanzania made great improvements in the renal replacement therapy infrastructure and services. However, renal replacement therapy remains a challenge in the developing world in terms of inadequate renal registries, and limited published literature. Objectives: This study will identify predictors of mortality, identify common causes …

renal replacement therapy
renal failure
dialysis
kidney replacement
nephropathy
  • 0 views
  • 25 Jan, 2021
  • 1 location
The Need for Repeat ERCP After Endoscopic Treatment of Postsurgical Biliary Leaks

Post-surgical biliary leaks are relatively common after surgeries associated with hepatobiliary health. Left untreated, biliary leaks can lead to significant morbidity. Biliary leaks are most often successfully managed endoscopically, by way of performing an ERCP (endoscopic retrograde cholangio-pancreatography) procedure. These procedures help manage the bile leak by decreasing pressure at …

  • 0 views
  • 08 Dec, 2021
  • 1 location