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Found 21 clinical trials
Testosterone Therapy in Men With Low Testosterone Levels and Metabolic Syndrome or Early Stages of Type 2 Diabetes

Men with metabolic syndrome often have lower than normal testosterone levels and low testosterone levels have been suggested to predispose for development of type2 diabetes. The aim of the study is to evaluate if normalisation of serum testosterone levels in men with metabolic syndrome (Abdominal obesity, hypertension, dyslipidemia, insulin resistance …

blood pressure diastolic
type 2 diabetes mellitus
diabetes
systolic blood pressure
fasting
  • 232 views
  • 07 Nov, 2020
  • 1 location
bpMRI and Risk Based Shared Clinical Decision Making in Prostate Cancer Diagnosis

The shortcoming of the pre-biopsy prostate MRI approach is the recommendation to biopsy all men post-MRI even if there is no lesion seen in MRI, ie. risk of PCa is very low. Therefore, the primary objective of this trial is to compare if there is a difference between significant cancer …

biopsy of prostate
digital rectal examination
  • 0 views
  • 27 Jan, 2021
  • 5 locations
Comparative Health Research Outcomes of NOvel Surgery in Prostate Cancer

Men diagnosed with significant cancer confined to the prostate currently undergo radical therapy directed to the whole prostate (radiotherapy or prostatectomy). These provide good cancer control but can cause significant side effects. Focal Therapy involves targeting the cancer alone, whilst leaving healthy prostate gland alone. Case series have shown similar …

prostatectomy
adenocarcinoma
antiandrogens
brachytherapy
bicalutamide
  • 2 views
  • 25 Apr, 2021
  • 10 locations
Prostate Screening Study Using MRI in BRCA Carriers

BRCA mutation includes PSA testing and digital rectal examination (DRE), the same as with men in the general population. This study is being done to assess whether there is value in using MRI as

transrectal ultrasound
digital rectal examination
BRCA2
BRCA1
  • 11 views
  • 16 Apr, 2021
  • 1 location
Extended Systematic Versus Mri-Assisted pRostate Transperineal Biopsy

with or without abnormal digital rectal examination (DRE) will be randomized in a 1:1 manner to MRI-arm or TP-arm. In the MRI-arm, multiparametric MRI prostate will be performed for each subject. MRI

  • 0 views
  • 26 Jun, 2021
  • 5 locations
Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies Radiotherapy & Surgery

This is a prospective phase II study to assess the efficacy and toxicity of HSV-tk+ valacyclovir gene therapy in combination with androgen deprivation therapy, brachytherapy, external beam radiotherapy, and prostatectomy in previously untreated high-risk prostate cancer.

leuprolide
prostatectomy
metastasis
adenocarcinoma
brachytherapy
  • 3 views
  • 13 Apr, 2021
  • 1 location
Digital PET/CT Using [Ga-68]PSMA for Characterization of Prostate Lesions

The purpose of this study is to evaluate a radioactive diagnostic study drug, which is called Gallium-68 Prostate Specific Membrane Antigen ([Ga-68]PSMA) for characterization of prostate abnormalities.

  • 0 views
  • 09 Jul, 2021
  • 1 location
Administration of Antibiotic Prophylaxis for Transperineal Prostate Biopsy in Cipto Mangunkusumo Hospital

This randomized controlled trial aims to compare the rate of perioperative infection complications in transperineal prostate biopsy between the group that receives prophylactic antibiotic and the group that receives placebo. The types of infection studied included bacteriuria, urinary tract infection (UTI), UTI with fever (febrile UTI), and sepsis. This study …

sepsis
trimethoprim-sulfamethoxazole
antibiotics
bacteriuria
fever
  • 0 views
  • 12 Aug, 2021
  • 1 location
BReak Interval Delayed Surgery for Gastrointestinal Extraperitoneal Rectal Cancer

This is a randomized multicentric clinical trial in patients affected by resectable rectal cancer, cT2N1-2, cT3N0-2, MRF -, aiming to evaluate the impact of the interval between chemoradiotherapy and surgery on the pathological response. Patients will undergo a neoadjuvant chemoradiotherapy treatment and those achieving a major or complete clinical and …

  • 0 views
  • 22 Feb, 2021
  • 1 location
Early Detection of Prostate Cancer

This study is the early detection of prostate cancer by analysing circulating bloodbased biomarkers. Based on our latest developments, we primarily aim to assess the validity of CTCs (circulating tumour cells) and tumour cell products circulating in blood (DNA, exosomes) for early PCa (Prostate cancer) detection. In the first discovery …

  • 0 views
  • 07 Mar, 2021
  • 3 locations