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Found 17 clinical trials
5% KOH Solution vs. Placebo and Diclofenac Gel for the Treatment of Actinic Keratosis

hydroxide solution (Solcera, medical device) versus placebo and investigator-blinded comparison with 3% diclofenac gel (Solaraze, medicinal product). It is performed in accordance with both the laws in

  • 11 Nov, 2021
  • 18 locations
Electroacupuncture vs Topical Diclofenac Sodium Gel for Patients With Hand Osteoarthritis

OA exist. Diclofenac sodium gel (DSG) is one of the commonly used topical NSAIDs, which can provide local pain relief for patients with hand OA with reduced systemic exposure, potentially reducing

  • 25 Jan, 2021
  • 1 location
Trichloroacetic Acid as a Topical Treatment for Actinic Cheilitis

, imiquimod, ingenol mebutate and diclofenac. More recently, photodynamic therapy has been brought forward as a potential treatment modality. From a surgical perspective, a vermilionectomy is typically the

  • 22 Aug, 2021
  • 1 location
Opioid Based Analgesia vs Non-opioid Analgesia for Oocyte Retrieval Procedure

It is unclear whether routine addition of opioids for analgesia during minor gynecological procedures is beneficial. In this single-center randomized single-blinded trial, the investigators aim to test the primary hypothesis that opioid-sparing anesthesia regimen including intravenous acetaminophen is non-inferior to a similar anesthesia regimen containing fentanyl in providing postoperative analgesia …

  • 17 Dec, 2021
  • 1 location
Decompression of Odontogenic Cysts Using an Appliance Fabricated With a Fully Digital Workflow

The aim of this prospective case series is to present clinical results with cystostomy, decompression and final enucleation of odontogenic cysts using a decompression device fabricated with a full digital workflow and delivered on the day of cystostomy. The secondary purpose of our study is to present the volumetric changes …

  • 10 Mar, 2022
A Randomized, Parallel-Group, Single-Attack, Open-Label Study to Evaluate the Efficacy of Diclofenac Potassium and Rimegepant for the Acute Treatment of Migraine (ATOM) (ATOM)

In a real-world population of adults with migraine, the investigators would like to investigate whether 50 mg diclofenac potassium is non-inferior to 75 mg rimegepant in terms of pain freedom at

  • 19 Oct, 2022
  • 1 location
Acute Low Back Pain. Topical Diclofenac and Oral Ibuprofen.

This is a randomized, double-blind study comparing two different treatments for acute low back pain, oral ibuprofen and topical diclofenac. Participants will be randomized to one of three study

back pain
radicular pain
low back pain
  • 23 Mar, 2022
  • 1 location
Efficiency and Safety a Fixed Combination of Orphenadrine and Diclofenac for Postoperative Analgesia

of 30 mg of orphenadrine and 75 mg of diclofenac; the second group will consist of 30 patients who will use patient-controlled morphine analgesia (РСА) in the form of monotherapy.

Accepts healthy volunteers
  • 27 Apr, 2022
  • 1 location
Topical Diclofenac and Topical DFMO Chemoprevention Trial in Subjects With a History of Skin Cancer

This is a single institution, randomized, placebo-controlled, double-blind phase IIB trial of topical diclofenac and topical DFMO, or 2) placebo in participants with a history of

  • 11 Mar, 2022
  • 2 locations
Study of PK and Safety of the LicartTM Topical System in Pediatric and Adult Participants With Minor Soft Tissue Injury

A multi-center, prospective, open-label, controlled study of the pharmacokinetics and safety of the LicartTM topical system in pediatric and adult participants with minor soft tissue injuries. 150 male and female participants aged 6-16 and 18-45 with soft tissue injuries meeting the following criteria will be enrolled to evaluate the pharmacokinetics …

  • 23 Mar, 2022
  • 5 locations