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Found 68 clinical trials
Molecular Analysis of Diabetic Kidney Disease Biopsies

Despite decades of research, the pathogenesis of human diabetic kidney disease remains largely unclear. Our goal is to use archived human kidney biopsy tissue from patients with and with

diabetes
nephropathy
diabetic nephropathy
type 2 diabetes mellitus
glomerulosclerosis
  • 13 views
  • 13 Feb, 2022
  • 1 location
Diabetic Nephropathy in People With Diabetes. Prevalence and Predictive Factors (PRIMETIME2)

a prospective, observational, multi-center study with a cohort of 300 patients with Type 2 diabetes and macroalbuminuria. Prospectively we will collect kidney biopsies and analyse the transciptome of the kidney tissue and other biomarkers from blood, faeces, urine, proteomicand metabolomic profiles and DNA-variants. Thereby we hope to be able to …

diabetes
kidney biopsy
nephropathy
diabetic nephropathy
albumin/creatinine ratio
  • 0 views
  • 19 Apr, 2022
  • 2 locations
An Observation Study to Evaluate the Renoprotective Effect of Fimasartan in Patients With DKD and Proteinuria

This study aims to observe changes in various indicators of renal function, such as proteinuria at different time points: short-term (Week 8), 6 months (Week 26), and a year (Week 52), in patients with DKD and hypertension, who are given antihypertensives containing fimasartan, in an actual clinical environment where a …

diabetes
kidney function tests
renal function
hypertension
proteinuria
  • 0 views
  • 30 Oct, 2021
  • 1 location
MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus (MERMAID-T1D)

In type 1 diabetes (T1DM), automated insulin delivery (AID) systems such as the hybrid closed loop artificial pancreas (HCL AP) combine the use of an insulin pump, continuous blood sugar monitor, and control algorithm to adjust background insulin delivery to improve time in target blood sugar range. Systems such as …

diabetes
kidney function tests
type 1 diabetes mellitus
hdl cholesterol
sugars
  • 0 views
  • 04 Oct, 2022
  • 1 location
Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)

Early diabetic kidney disease (DKD) occurs in 50-70% of youth with type 2 diabetes (T2D) and confers high lifetime risk of dialysis and premature death. Youth-onset T2D typically manifests

diabetes
prediabetes
Accepts healthy volunteers
dialysis
insulin
  • 0 views
  • 25 Mar, 2022
  • 1 location
The Effectiveness of Urine mtDNA and Beta 2-MG to Predict Acute Kidney Injury for Critically Ill Surgical Patients

studies) Mitochondria are involved in development and recovery of diabetic nephropathy. UmtDNA can be used as early marker to detect the development of AKI

nephropathy
  • 0 views
  • 04 Oct, 2022
  • 1 location
Value of Uric Acid as Early Predictor of Lupus Nephritis

The aim of the present work is to determine the role of uric acid as a predictor and prognostic factor in the development of lupus nephritis.

  • 0 views
  • 17 Jun, 2022
  • 1 location
Incidence and Predictors of Acute and Chronic Complications in Patients With Diabetes and Severe COVID-19

All surviving patients of the Michigan Medicine COVID-19 Cohort (M2C2, PI: Hayek) that were admitted to the University of Michigan for severe COVID-19 disease are eligible for this study. Investigators had prior approval from the Institutional Review Board (IRB) to collect the baseline blood and urine samples of these participants. …

cardiovascular disease
  • 0 views
  • 24 Mar, 2022
  • 1 location