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Found 68 clinical trials
Effects of Probiotics and Fibers on Albuminuria in Persons With Type 1 Diabetes (ProFOS)

The primary objective is to assess the impact of three months' treatment with pre-/probiotic mix on markers of nephropathy and other comorbidity related to diabetes. A double blinded, randomized, placebo-controlled crossover, single-centre study including 46 patients with type 1 diabetes and albuminuria. The treatment period is 2 x 12 weeks …

renin
insulin
diabetes
angiotensin
insulin treatment
  • 0 views
  • 23 Mar, 2022
  • 1 location
Effect of Heart-Protecting Musk Pill on Diabetic Microangiopaemia in Type 2 Diabetes Patients

The study mainly investigates the therapeutic effect of Heart-Protecting Musk Pill (HMP) on patients with diabetic microangiopathy. According to the indicators of diabetic nephropathy (DN

  • 0 views
  • 15 Oct, 2022
  • 1 location
Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes (IMPROVE-T2D)

adult-onset T2D, youth with T2D have a more aggressive phenotype with greater insulin resistance (IR), more rapid β-cell decline and higher prevalence of diabetic kidney disease (DKD), arguing for

cardiovascular disease
pancreatic failure
remission
diabetic nephropathy
sleeve gastrectomy
  • 97 views
  • 24 Mar, 2022
  • 1 location
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes (MANATEE-T1D)

Diabetic kidney disease and cardiovascular disease remain the leading causes of morbidity and mortality in people with type 1 diabetes and are exacerbated with longer duration of diabetes and

insulin resistance
cardiovascular disease
diabetes
Accepts healthy volunteers
glomerular filtration rate
  • 0 views
  • 04 Oct, 2022
  • 1 location
Effect of Taurine on Glycemic, Lipid and Inflammatory Profile in Individuals With Type 2 Diabetes (TAUGLIP-DM2)

, animal models showed that taurine had a protective effect from diabetic nephropathy. The hypothesize of this study is that taurine administration improves the glycemic, lipid, inflammatory, and

  • 0 views
  • 23 Mar, 2022
Stem Cell Therapy for Chronic Kidney Disease

The purpose of this study is to assess the safety and tolerability of allogeneic mesenchymal stem / stromal cell therapy in individuals with chronic kidney disease.

renin
angiotensin
aldosterone
glomerular filtration rate
  • 0 views
  • 11 Nov, 2021
  • 2 locations
A Series of Pilot Studies to Evaluate the haemoDynamic and mEtabolic Effects oF apelIn aNd rElaxin (DEFINE)

occurred prior to diagnosis. Diabetes is associated with the development of microvascular complications (diabetic nephropathy, neuropathy, and retinopathy), and macrovascular complications (coronary artery

coronary disease
arteriopathy
hypoglycemic agents
Accepts healthy volunteers
diabetic complication
  • 15 views
  • 14 Mar, 2022
  • 1 location
Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study (Renal-HEIR)

adult-onset T2D, youth with T2D have a more aggressive phenotype with greater insulin resistance (IR), more rapid β-cell decline and higher prevalence of diabetic kidney disease (DKD), arguing for

Accepts healthy volunteers
diabetic nephropathy
insulin
diabetic ketoacidosis
kidney biopsy
  • 9 views
  • 24 Mar, 2022
  • 1 location
Dapagliflozin in Non-diabetic Stage IV CKD

inhibitors may reduce the excess cardiovascular mortality associated with diabetic renal disease. In addition to RAS inhibitors, however, multimodal approaches including lifestyle modifications and multidrug

hemoglobin a1c
diabetes
  • 0 views
  • 08 Dec, 2021
  • 1 location
A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Immune Nephritis

A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Immune Nephritis

nephritis
  • 0 views
  • 30 Oct, 2021
  • 1 location