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Found 347 clinical trials
The Effect of Sodium-glucose Cotransporter (SGLT) 2 Inhibitors on Cystine Stone Formation: A Preliminary Study

hypothesized that a glucose molecule may be able to do this if introduced into the urine. SGLT-2 inhibitors are a class of drug that are FDA approved to treat diabetes mellitus (DM) and heart failure by

  • 0 views
  • 07 Apr, 2022
  • 1 location
Metabolic Phenotyping During Stress Hyperglycemia in Cardiac Surgery Patients

The study is a prospective randomized study to examine the effects of exposure to dulaglutide on the prevention of stress-hyperglycemia and the metabolic inflammatory response in the perioperative period

  • 0 views
  • 02 Aug, 2021
  • 3 locations
A Study to Evaluate THR-687 Treatment for Diabetic Macular Oedema. (INTEGRAL)

This study is conducted to select the THR-687 dose level (Part A of the study) and to assess the efficacy and safety of the selected dose level compared to aflibercept (Part B of the study).

aflibercept
sd-oct
diabetes
  • 4 views
  • 19 Apr, 2022
  • 26 locations
A Real-World Study of a Mobile Device-based Serious Health Game on Session Attendance in the National Diabetes Prevention Program

The overall prevalence of type 2 diabetes in the United States (US) is estimated at more than 30 million people, with an estimated 88 million more adults meeting the criteria for having prediabetes and being at risk for progressing to type 2 diabetes. The significant burden of diabetes, as well …

body mass index
diabetes prevention
Accepts healthy volunteers
  • 39 views
  • 18 Apr, 2022
  • 1 location
Enhanced Quality in Primary Care for Elders With Diabetes and Dementia (EQUIPED-ADRD)

The purpose of this study is to develop and test a care quality improvement intervention featuring use of consensus decisional guidance for the medical management of diabetes (DM) in patients

alzheimer's disease
dementia
cognitive impairment
  • 16 views
  • 03 Feb, 2022
  • 1 location
Clinic to Community Navigation to Improve Diabetes Outcomes (CCN)

Background and justification: Nearly 29 million Americans (9.3% of the population) have type 2 Diabetes Mellitus (T2DM) and another 86 million are considered prediabetic, 20-30% of whom will develop diabetes within five years.4,5 T2DM disproportionately affects those from lower socioeconomic status (SES) and rural backgrounds. Appalachian residents represent an extreme …

hypoglycemia
glycosylated hemoglobin
diabetes mellitus
hemoglobin a1c
type 2 diabetes mellitus
  • 190 views
  • 04 Mar, 2022
  • 1 location
A Study to Learn How Safe BAY2395840 is and How Well it Works in Participants Who Have Diabetic Nerve Pain

Researchers are looking for a better way to treat people who have diabetic neuropathic pain (DNP), a condition in which diabetes results in pain due to nerve damage. People with diabetes have high blood sugar levels. Over the time, high blood sugar levels can cause damage to the nerves in …

electrocardiogram
antidiabetic agents
sugars
type 2 diabetes mellitus
  • 0 views
  • 17 May, 2022
  • 16 locations
Intensive Versus Conventional Hyperglycemic Control in Hospitalized Non-critically Ill Patients

Hyperglycemia is a common condition among hospitalized patients. The occurrence of severe hyperglycemia is associated with increased morbidity and mortality in several populations. Several trials assessed the benefits of aggressive versus conventional glucose control. These studies evaluated different patient populations, glucose targets and treatment protocols and as a result reported …

hypoglycemia
hyperglycemia
diabetes mellitus
insulin
type 2 diabetes mellitus
  • 0 views
  • 03 Mar, 2022
  • 2 locations
A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema (KALAHARI)

Part A of the study is conducted to select the THR-149 dose level. Part B of the study is conducted to assess the efficacy and safety of the selected dose level compared to aflibercept, up to Month 3. As from Month 3, in about half of the subjects, the effect …

sd-oct
edema
diabetic macular edema
optical coherence tomography
aflibercept
  • 20 views
  • 25 Apr, 2022
  • 48 locations
Early Detection Initiative for Pancreatic Cancer (EDI)

The Early Detection Initiative for Pancreatic Cancer is a multi-center randomized controlled trial to determine if algorithm-based screening in patients with new onset hyperglycemia and diabetes can result in earlier detection of pancreatic ductal adenocarcinoma.

hyperglycemia
oral glucose tolerance test
hemoglobin a1c
fasting blood glucose
fasting
  • 0 views
  • 27 Apr, 2022
  • 2 locations