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Found 4 clinical trials
Neurotoxicity Prophylaxis With Intrathecal Dexamethasone and Simvastatin Post Axi-Cel

Open-label, single-arm, single center pilot study to assess safety and feasibility of administering dexamethasone intrathecally and simvastatin orally during axicabtagene ciloleucel (axi-cel) treatment. Feasibility will be measured by the proportion of patients completing two-thirds (2/3) of their assigned treatments. The study will be deemed feasible if 2/3 or more of …

chemotherapy regimen
follicular lymphoma
diffuse large b-cell lymphoma
  • 02 Sep, 2021
  • 1 location
IPACK or Selective Tibial Nerve Block for ACL Reconstruction With an Adductor Canal Block (TIPACK)

The purpose of this study is to compare the analgesic efficacy of the combination of an adductor canal and selective tibial nerve blocks versus adductor canal block and IPACK after ACL reconstruction under general anaesthesia.

  • 25 Jul, 2022
  • 1 location
A Prospective Pilot Study of a Non-Narcotic Post-Operative Course After Colectomy

With this pilot investigation, the investigators aim to challenge the reliance on opiate analgesia following colon and rectal surgery. Narcotic misuse and abuse is a pressing public health concern, and reduction in prescription rates could help to mitigate this issue. The goal of this pilot study is to establish feasibility …

pain relieving
Accepts healthy volunteers
  • 05 Jun, 2022
  • 1 location
Impact of a Minimally Invasive Approach to Laparoscopic Hysterectomy on Postoperative Recovery

Background Managing perioperative stress, including endocrino-metabolic changes and, inflammatory and pain responses, is a major challenge to improve patient's recovery. Currently, minimally invasive surgical procedures combined with multimodal analgesia are commonly used to increase the quality of postoperative period. Purpose To demonstrate that a minimally invasive approach including low insufflation …

  • 09 Nov, 2021
  • 1 location