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Found 206 clinical trials
Efficacy of Esomeprazole in Children and Adolescents With Autism Spectrum Disorder

This treatment study of esomeprazole in ASD will be the first study in the world with significant originality and innovation. The investigators anticipate seeing the effect of esomeprazole on improving the core symptoms of ASD, particularly within the social communication and cognition domains.

  • 523 views
  • 08 Nov, 2020
  • 1 location
Translational Research to Inform Interventions for Challenging Behavior

This project is meant to identify relations between the reinforcement histories of 80 adults with intellectual and developmental disabilities (IDD) and the prevalence of extinction bursts

Accepts healthy volunteers
  • 0 views
  • 10 Oct, 2021
  • 2 locations
Effects of Emotional Processes on Speech Motor Control in Early Childhood Stuttering.

This study will compare speech variability between preschool-age children who stutter and typically fluent, age-matched peers. Differences in emotional reactivity, regulation and speech motor control have been implicated in stuttering development in children. This study seeks to understand further how these processes interact. Children will repeat a simple phrase after …

Accepts healthy volunteers
  • 0 views
  • 01 May, 2022
  • 1 location
A Brief Emotion Focused Therapy for Preschoolers With Anxiety Disorders

The study will comprise of three groups of children (n=40): 1. A group receiving a novel short-term dynamic play therapy. 2. Dyadic therapy 3. Control group who will not receive therapy. All children will be assessed for psychopathology (anxiety, depression and behavioral problems) using standardized instruments such as semi-structured interview …

  • 0 views
  • 10 Aug, 2021
  • 1 location
Digital Epidemiology Study on Brain Functioning in Children Aged 7 to 12 Years (EPIDIA4Kids)

Neurobiology has improved the integrative understanding of brain development. With digital technologies, digital (bio)markers would be relevant variables for a better understanding of the heterogeneity of cognitive and behavioral functioning in developing children. However, the dominant statistical approach of group comparison tends to ignore intragroup variability. Applying high-dimensional data sets …

Accepts healthy volunteers
  • 0 views
  • 22 Oct, 2022
Addressing Disparities in Autism Spectrum Disorder Diagnosis Using a Direct-to-home Telemedicine Tool

The investigators propose to evaluate the use of a telemedicine tool, the TELE-ASD-PEDS (TAP), that is designed to assess for autism spectrum disorder (ASD) symptoms in toddlers. The TAP was developed at VUMC by a team of clinical psychologists with expertise in the early identification of ASD. The TAP has …

  • 0 views
  • 16 Jun, 2022
  • 1 location
An Exploratory, Phase 2, Randomized, Double-blind, Placebo-controlled Trial to Investigate the Safety and Efficacy of Cannabidiol Oral Solution (GWP42003-P; CBD-OS) in Children and Adolescents With Autism Spectrum Disorder

This study will be conducted to evaluate the efficacy of GWP42003-P, compared with placebo, in reducing symptom severity in children with Autism Spectrum Disorder (ASD).

  • 26 views
  • 21 Oct, 2022
  • 16 locations
Probiotic Therapy for Children and Adults With Autism Spectrum Disorder

This is a study of the effect of a customized probiotic on children and adults with autism, including effects on autism symptoms and gastrointestinal symptoms.

  • 14 views
  • 08 Jan, 2022
  • 1 location
A Phase II Multicenter, Randomized, Double-Blind, 12-Week Treatment, 3-Arm, Parallel-Group, Placebo-Controlled Study to Investigate the Efficacy, Safety, and Tolerability of RO7017773 in Participants Aged 15-45 Years With Autism Spectrum Disorder (ASD)

This study will investigate the efficacy, safety, tolerability, and pharmacokinetics of RO7017773 in participants aged 15-45 years who have been diagnosed with ASD with a score of >/=50 on the Wechsler Abreviated Scale of Intelligence (WASI-II).

  • 38 views
  • 23 Oct, 2022
  • 20 locations
Early Screening of Autism Spectrum Disorder in General and Pediatric Practices (KitCAT)

Early screening for Autism Spectrum Disorder has been validated using different screening tools, in particular M-CHAT-R and ITC in different countries. Unfortunaltely, in France, they are not often used. Thus, medium age for diagnosis in France is late. Yet, early interventions has shown efficiency (grade B of HAS 2010 recommendations, …

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csbs
autism
pervasive developmental disorder
Accepts healthy volunteers
  • 42 views
  • 04 Oct, 2022
  • 1 location