Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 13 clinical trials
A Study of AL102 in Patients With Progressing Desmoid Tumors (RINGSIDE)

The current study is designed to evaluate the efficacy and safety of AL102 in patients with progressive desmoid tumors.

measurable disease
line of therapy
MRI
  • 11 views
  • 01 Jul, 2022
  • 27 locations
A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery

This phase II trial studies the side effects and how well nirogacestat works in treating patients patients less than 18 years of age with desmoid tumors that has grown after at least one form of

imatinib
stroke
nonsteroidal anti-inflammatory drugs
tumor cells
tamoxifen
  • 0 views
  • 10 Aug, 2022
  • 51 locations
Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies

This is a phase I/II, non randomized, open-label, dose escalation study to investigate the safety, tolerability and preliminary efficacy of CB-103.

calcium
lipase
cytotoxic chemotherapy
cancer chemotherapy
marginal zone lymphoma
  • 286 views
  • 25 Mar, 2022
  • 14 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

>Desmoid tumors Peripheral nerve sheath tumors and NF1-related tumors (closed to accrual 09/19/2018) Malignant giant cell tumors Chordoma (closed to accrual 11/29/2018)

pituitary
solid tumors
mullerian mixed tumor
lipase
pheochromocytoma, malignant
  • 6634 views
  • 10 Aug, 2022
  • 752 locations
Cryotherapy in the Treatment of Desmoid Tumors

Desmoid tumor is a benign neoplasm with an unpredictable course and a high rate of local recurrence if treated surgically. Therefore, over time the surgical approach has become conservative

measurable disease
nonsteroidal anti-inflammatory drugs
tamoxifen
hormone therapy
medical therapy
  • 0 views
  • 22 Apr, 2022
  • 1 location
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits of tegavivint in treating patients with solid tumors that has come back (recurrent) or does not respond to treatment (refractory). Tegavivint interferes with the binding of beta-catenin to TBL1, which may help stop the growth of …

cancer chemotherapy
cytotoxic chemotherapy
donor lymphocyte infusion
glomerular filtration rate
blood count
  • 0 views
  • 09 May, 2022
  • 10 locations
A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor

This is a phase I/II, open-label, non-randomized, multicentre study to evaluate the clinical activity of vactosertib plus imatinib in desmoid tumor. Based on the background, TGF-β inhibition as

imatinib
measurable disease
fibromatosis
ejection fraction
vactosertib
  • 46 views
  • 02 Jul, 2022
  • 1 location
Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma (TNT)

This is a Phase 2 study using talimogene laherparepvec, nivolumab, and trabectedin as first, second or third line therapy for advanced sarcoma, including desmoid tumor and chordoma.

metastatic sarcoma
measurable disease
kidney function tests
trabectedin
advanced sarcoma
  • 37 views
  • 08 Feb, 2022
  • 1 location
Safety and Efficacy Study Using 5-ALA Oral Administration as an Adjuvant Therapy on the Rate of Local Tumor Recurrence in Patients Who Have Desmoids Tumors

therapy on the 3 years rate of local tumor recurrence in patients with desmoid tumors. To evaluate the Safety of 5-ALA administration. 5 years local recurrence rate.

  • 39 views
  • 08 Nov, 2020
  • 1 location
HIFU Ablation of Soft Tissue Sarcoma (SarcAblate)

> This study will recruit patients with both resectable and unresectable STS, in addition to unresectable small symptomatic desmoid tumours. 12-16 patients, and a minimum of 10 patients with

cancer chemotherapy
cancer
soft tissue sarcoma
  • 0 views
  • 21 Mar, 2022
  • 1 location