Found 13 clinical trials
Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies
This is a phase I/II, non randomized, open-label, dose escalation study to investigate the safety, tolerability and preliminary efficacy of CB-103.
- 281 views
- 26 Jan, 2021
- 12 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
>Desmoid tumors Peripheral nerve sheath tumors and NF1-related tumors (closed to accrual 09/19/2018) Malignant giant cell tumors Chordoma (closed to accrual 11/29/2018)
- 6048 views
- 24 Sep, 2021
- 818 locations
Doxorubicin Eluting Intra-arterial Embolization for Aggressive Desmoid Fibromatosis
In this study Drug-eluting microbeads (DEB) loaded with Doxorubicin will be delivered into the target Desmoid Fibromatoses (DF) tissue via selective arterial embolization by angiographic
- 17 views
- 23 Jan, 2021
- 1 location
A Study of AL102 in Patients With Progressing Desmoid Tumors
The current study is designed to evaluate the efficacy and safety of AL102 in patients with progressive desmoid tumors.
- 0 views
- 10 Sep, 2021
- 10 locations
A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor
This is a phase I/II, open-label, non-randomized, multicentre study to evaluate the clinical activity of vactosertib plus imatinib in desmoid tumor. Based on the background, TGFinhibition as a
- 45 views
- 01 May, 2021
- 1 location
A Study of a New Drug Nirogacestat for Treating Desmoid Tumors That Cannot be Removed by Surgery
This phase II trial studies the side effects and how well nirogacestat works in treating patients patients less than 18 years of age with desmoid tumors that has grown after at least one form of
- 0 views
- 12 Sep, 2021
- 42 locations
Talimogene Laherparepvec Nivolumab and Trabectedin for Sarcoma
This is a Phase 2 study using talimogene laherparepvec, nivolumab, and trabectedin as first, second or third line therapy for advanced sarcoma, including desmoid tumor and chordoma.
- 1 views
- 26 Aug, 2021
- 1 location
Safety and Efficacy Study Using 5-ALA Oral Administration as an Adjuvant Therapy on the Rate of Local Tumor Recurrence in Patients Who Have Desmoids Tumors
therapy on the 3 years rate of local tumor recurrence in patients with desmoid tumors. To evaluate the Safety of 5-ALA administration. 5 years local recurrence rate.
- 39 views
- 08 Nov, 2020
- 1 location
Nivolumab (Opdivo ) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers
sarcoma, PEComa, epithelioid sarcoma, desmoid tumor, chordoma, non-small cell lung cancer, small cell lung cancer, urethelial carcinoma, melanoma, renal cell carcinoma, squamous cell carcinoma of head and
- 82 views
- 15 May, 2021
- 1 location
MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors
The purpose of this study is to determine if Magnetic Resonance guided High Intensity Focused Ultrasound ablative therapy is safe and feasible for children, adolescents, and young adults with refractory or relapsed solid tumors.
- 274 views
- 07 Aug, 2021
- 2 locations
- 1
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