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Found 353 clinical trials
A Study to Evaluate the Efficacy and Safety of CBP-201 in Moderate to Severe Atopic Dermatitis in China

This study will evaluate the efficacy and safety of CBP-201 in Chinese adult subjects with moderate to severe atopic dermatitis.

  • 0 views
  • 29 Sep, 2021
  • 32 locations
A Study of a Probiotic Food Supplement Containing B. Infantis (EVC001) in Healthy Breastfed Infants at Risk of Developing Atopic Dermatitis

The purpose of this study is to assess the effect of B. infantis (EVC001) versus placebo supplementation, in healthy breastfed infants at risk of developing atopic dermatitis (AD), on cumulative

Accepts healthy volunteers
  • 2 views
  • 03 May, 2022
  • 1 location
Epidermal Skin Grafts to Improve Healing In Radiation Wounds

Patients undergoing radiation for the treatment of malignancies may suffer from side effects to the skin in the form of radiation dermatitis. This can lead to local wound formation with poor

  • 0 views
  • 02 Feb, 2021
A Pilot Study of the Efficacy and Safety of Dupilumab Versus Placebo in Patients With Netherton Syndrome

To date, there are no effective therapy for the management of Netherton Syndrome (NS) Patients use emollients with a limited efficacy on scaling and no efficacy on skin inflammation and pruritus

  • 0 views
  • 12 Sep, 2021
  • 2 locations
Efficacy and Safety of Dupilumab Chronic Hands Eczema Refractory to Highly Potent Topical Corticosteroids

Dupilumab has recently demonstrated high efficacy and good safety profile in the treatment of moderate-to-severe atopic dermatitis. There is a crucial need of developing new treatment options in

  • 0 views
  • 12 Sep, 2021
  • 3 locations
Multi-Center PAMPA Study (PAMPA)

-biologic standard of care. The primary objective of our proposed trial will be to test the hypothesis that a prolonged, unresolved skin inflammation coupled with musculoskeletal power-doppler

guselkumab
  • 0 views
  • 03 May, 2022
  • 2 locations
Study of Dupilumab to Demonstrate Efficacy in Subjects With Nummular Eczema

inhibiting the IL-4 and IL-13 pathway by targeting the IL-4-receptor, has been approved for the treatment of moderate-to-severe atopic dermatitis (AD). Since there is an overlap between AD and NE with both

  • 0 views
  • 29 Mar, 2021
  • 1 location
Alternation in the Human Microbiome With Commonly Used Topical Medications

The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: Investigate whether ketoconazole cream, a commonly used topical antifungal, causes alterations …

Accepts healthy volunteers
  • 128 views
  • 26 Feb, 2022
  • 1 location
Cholinergic Urticaria - Efficacy of Dupilumab (CHED)

The purpose of this study is to assess the efficacy in reducing disease activity and safety of Dupilumab in adult patients with cholinergic urticarial (CholU) who are symptomatic despite H1-antihistamine treatment (licensed dose).

  • 68 views
  • 25 Mar, 2022
  • 7 locations
Dupilumab Severe Eosinophilic Chronic Sinusitis Without Nasal Polyposis

The investigators will investigate the efficacy of dupilumab in patients with severe eosinophilic CRSsNP who are resistant to the conventional treatment with intranasal corticosteroids and have significantly extensive disease involving more than 2 sinuses bilaterally in sinus CT scan and Lund-Mackay sinus (LMK) CT score >=10 at baseline.

  • 2 views
  • 16 Aug, 2021
  • 1 location