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Found 393 clinical trials
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New Orleans Pulmonary Hypertension Biobank

Pulmonary hypertension (PH) is a serious condition characterized by a mean pulmonary artery pressure >=25mmHg on right heart catheterization (RHC). Despite advances in PH care, outcomes are still sub-optimal and further research is required into the pathobiology of the disease and development of biomarkers that can guide clinical care. The …

systemic sclerosis
rheumatism
right heart catheterization
hypertension
mixed connective tissue disease
  • 114 views
  • 18 Sep, 2021
  • 1 location
None
Acetylated Natural Nucleotides in Treating Hand-foot Syndrome

The clinical trial is planned to investigate the efficacy and safety of acetylated natural nucleotides in treating anti-cancer medications induced hand-foot syndrome (HFS).

  • 0 views
  • 19 Jul, 2021
  • 1 location
None
Hydration Based on Thoitaine Aloe Vera and Calendula in the Prevention of Hand-Foot Syndrome in Patients Using Capecitabine

Hand-foot syndrome (HFS) is a very common adverse event of many chemotherapeutic agents, especially capecitabine. The HFS can considerably interfere patient quality of life (QoL). The current treatments for hand-foot symptoms no have demonstrated 100% efficacy. And, the dose reduction and treatment interruption are recommended for treatment of HFS. It …

  • 0 views
  • 12 Apr, 2021
  • 1 location
None
G-CSF in the Treatment of Toxic Epidermal Necrolysis

NeupoNET aims to evaluate interest of G-CSF in the treatment of Toxic Epidermal necrolysis. This is a prospective randomized controlled trial. Patients will be allocated in a treatment group (receiving an injection of 5 microg/kg/d of G-CSF during 5 consecutive days) or in a placebo group. Patients will be randomized …

  • 15 views
  • 27 Jan, 2021
  • 4 locations
None
Monitoring Skeletal Muscle Mass Using CBCT in Patients With H&N Cancer Undergoing Chemoradiotherapy

Chemoradiotherapy is the standard treatment for unresectable locally advanced head and neck cancer (HNC). However, malnutrition is present in 44-88% HNC patients during chemoradiotherapy, which leads to loss of skeletal muscle mass (SMM) and poor clinical outcomes. Timely assessment of SMM and early intervention of malnutrition are particularly important for …

chemoradiotherapy
intensity-modulated radiation therapy
oropharyngeal
  • 0 views
  • 08 Dec, 2021
  • 1 location
None
Does Topical Steroid Treatment Impair the Adrenal Function?

The purpose of this study is to determine if topical steroids treatment for different skin diseases suppress the adrenal cortisol production.

  • 1 views
  • 07 Nov, 2020
  • 1 location
None
Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis

The investigators' aim is to study the effects of mechanical expression of meibomian glands on eyelid disease, ocular surface health in the subacute phase of SJS/TEN. The primary outcome is to use meibomian gland imaging to assess the health and caliber of the meibomian glands of both lower eyelids, between …

Accepts healthy volunteers
  • 0 views
  • 08 Dec, 2021
None
Links Between Inflammation and Cardiometabolic Diseases

Background Cardiometabolic diseases are a combination of medical disorders that, when they occur together, increase the risk of heart disease and diabetes. Researchers want to learn if there is a relationship between these diseases and inflammation (redness, swelling, and pain). Inflammation affects the entire body. Researchers will study this relationship …

electrocardiogram
diuretics
diabetes
Accepts healthy volunteers
angina pectoris
  • 356 views
  • 26 Nov, 2021
  • 1 location
None
The Role of Filaggrin Mutations and Sensitization Pathways in Allergic Rhinitis and Peanut Allergy

Caucasian male and female participants age 18 years of age and older will be enrolled in this study if they have known birch or peanut allergies or known to be non-atopic. Participants will undergo skin testing to confirm their allergies if not completed in the last 12 months. Medications and …

rhinitis
sensitisation
sensitization
skin test
atopy
  • 14 views
  • 25 Jan, 2021
  • 1 location
None
Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome Sjogren's Syndrome and Graft Vs Host Disease

The goal of this research is to determine if the Tangible Boost system adequately replenishes the Hydra-PEG coating on the surface of a rigid contact lens. Hydra-PEG is a coating for soft and rigid contact lens, primarily composed of polyethylene glycol-based hydrogel, which is covalently bound to the surface of …

  • 0 views
  • 08 Apr, 2021
  • 1 location