Found 335 clinical trials
Inflammatory Profiling in Chronic Lung Disease
The aim of this study is to investigate the underlying inflammatory profile in patients with chronic lung disease and determine the association pulmonary hypertension.
- 0 views
- 27 Jan, 2021
- 1 location
Study Roles of Heavy Metals and Essential Metal Dyshomeostasis in Pulmonary Arterial Hypertension Patients
Investigators plan to recruit 50 PAH patients from UofL PAH Clinic, with various degrees of severity (25 intermediate risk patients and 20 high risk patients) and 10 age and gender matched controls. PAH patients are evaluated at least every 6 months by the PAH Clinic and blood/urine samples will be …
- 19 views
- 23 May, 2022
- 1 location
Opioid-Redox Study (ORS)
caused by the effects of opioids are urticaria, dermatitis, and pruritus. Renal and urinary disorders may develop as urinary retention and ureteral spasm. Rarely can occur disorders of the immune system
- 80 views
- 24 Feb, 2022
- 1 location
Genetic and Environmental Determinants That Control Metabolism in Pulmonary Hypertension
The investigators are performing this research study to determine whether having low iron-sulfur cluster levels can cause a disease known as pulmonary hypertension (PH). PH is defined as abnormally high blood pressure in the arteries of the lungs. Usually, small specialized structures inside each human cell called mitochondria are in …
- 18 views
- 25 May, 2022
- 1 location
Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
Background High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a rare disorder. Some people have disease-associated PAH and some have PAH from an unknown cause. Researchers want to follow the natural history of all PAH patients to understand how PAH progresses in order to discover …
- 61 views
- 20 Jul, 2022
- 1 location
Exercise Hemodynamic Right Ventricular Coupling and Echocardiography in Pulmonary Hypertension
This study aims to investigate the exercise profile in pulmonary hypertension patients with either pulmonary arterial hypertension, chronic thromboembolic pulmonary hypertension or pulmonary hypertension due to left heart disease and in disease control.
- 0 views
- 14 Nov, 2021
- 2 locations
Right Atrial Fibrosis in Pulmonary Hypertension
The study aim to assess right atrial (RA) remodeling, in terms of RA fibrosis, in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension patients. This will be investigated in detail with in-depth cardiac magnet resonance imaging (CMRI). A cohort with exclusion of pulmonary hypertension which underwent CMRI due to dyspnoe …
- 0 views
- 17 Nov, 2021
- 2 locations
Neuregulin-1 in Patient With Different Forms of Cardiovascular Diseases: a Pilot Study (NRG-1-CVDs)
This is an observational study of Neuregulin-1 (NRG-1) plasma levels in patients with different forms of cardiovascular disease including microvascular angina (MVA), heart failure with preserved ejection fraction (HFpEF), as well as, heart failure with reduced ejection fraction (HFrEF) and pulmonary hypertension (PH). Investigators intend to identify cardiovascular diseases which …
- 0 views
- 08 Aug, 2022
- 1 location
Characteristics of Pulmonary Vascular Changes in Patients With Kidney Transplantation
The aim of the study is to investigate pulmonary hemodynamics at rest and during exercise in patients before and after kidney transplantation.
- 0 views
- 18 Apr, 2021
- 1 location
Acetylated Natural Nucleotides in Treating Hand-foot Syndrome
The clinical trial is planned to investigate the efficacy and safety of acetylated natural nucleotides in treating anti-cancer medications induced hand-foot syndrome (HFS).
- 0 views
- 18 Dec, 2021
- 1 location