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Found 69 clinical trials
Assessement of Capacity to Consent

give consent in the context of a severe depressive episode. This is a Social and Human Sciences study which does not aim to modify the usual management of patients.

  • 26 May, 2021
  • 1 location
Neuroinflammation in COVID-19 and Depression

The purpose of this study is to use state of the art brain imaging technology to investigate neuroinflammation in participants with depression after the respiratory symptoms of COVID-19 have passed.

  • 01 May, 2021
  • 1 location
The Effects of Anger and Joy Expressions on Approach and Avoidance Behaviors in Healthy Volunteers

Social interactions are part of our daily lives. Communicating with others is a recurring choice which is based on emotional cues, such as facial expression. Our action must be adapted to the emotional state of our interlocutor, otherwise the investigators will have poor quality interactions An emotional stimulus would cause …

  • 18 Sep, 2021
  • 1 location
Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder

Lithium is highly effective in the treatment of bipolar disorder. This study aims to investigate, for the first time, the impact of lithium monotherapy on the structural and functional connectivity of the brain using MRI imaging.

depressive episode
  • 12 Jul, 2021
  • 1 location
A Study of Pregnant and Postpartum Women With and Without Mood Disorders

This study is looking at genetic, biological, and environmental causes and how all three may work together to cause postpartum mood episodes. Participants will have psychiatric histories taken and will be monitored throughout pregnancy and during the postpartum period for the development of depressive or other mood episodes. Biological measures, …

mood disorder
  • 26 Jan, 2021
  • 1 location
The Sunnybrook Type 2 Diabetes Study

The Sunnybrook Type 2 Diabetes Study (S2DS) is a prospective observational study of people with prediabetes or Type 2 Diabetes Mellitus (T2DM), that aims to understand the aetiologies, manifestations, and clinical consequences of mood and cognitive complications. The study recruits from the services at Sunnybrook Health Sciences Centre and from …

impaired glucose tolerance
glycosylated hemoglobin
glucose intolerance
  • 24 Jan, 2021
  • 1 location
The Gut Microbiota of Bipolar and Depression

Background: The gut microbiome is emerging as an important factor in regulating mental health yet it remains unclear what the target should be for psychiatric treatment. Investigators aim at elucidating the complement of the gut microbiome community for individuals with Major Depressive disorder (MDD) and Bipolar disorder (BD) relative to …

depressive disorder
psychiatric treatment
major depressive disorder
bipolar disorder
  • 27 Aug, 2021
  • 1 location
Neurobehavioral Mechanisms of Emotion Regulation in Depression Across the Adult Lifespan

The aim of this study is to test a model of demographic (age, sex), clinical, cognitive, and neurocircuitry predictors of emotion regulation ability and long-term depressive symptoms.

depressive symptoms
  • 27 Jan, 2021
  • 2 locations
A Multicenter Prospective Non-interventional Observational Study to Evaluate the Quality of Life and Treatment of Anxiety Symptoms of Buspar Tab (Buspirone) in Patients With Depression in Korea

Approximately 20 sites in Korea including the Catholic University of Korea, Yeouido St. Mary's Hospital. Patients with major depressive disorder (MDD) taking a selective serotonin reuptake inhibitor (SSRI) antidepressant, who additionally administered Buspar Tab (Buspirone) to control symptom of anxiety. Primary objective: To evaluate the efficacy of treating the symptoms …

  • 05 Mar, 2021
  • 1 location