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Found 69 clinical trials
PREGBRAIN - Magnetic Stimulation of the Brain in Depressed Pregnant Women

for a moderate-severe depressive episode can be included. Participants will be randomized to either active or sham treatment. Treatment will be administered during 20 days, once daily (4 minutes per

  • 0 views
  • 12 May, 2021
  • 1 location
Delivering Electronic Cognitive Behavioural Therapy to Patients With Bipolar Disorder and Residual Depressive Symptoms

depressive episode will be recruited from the Mood and Anxiety Clinic at Providence Care Hospital in Kingston, Ontario, Canada. Eligible participants will then be randomly assigned to either the treatment

  • 0 views
  • 26 Jan, 2021
  • 1 location
The Effect of Celecoxib on Neuroinflammation in MDD

found that MDD patients in a current major depressive episode (MDE) had significantly higher TSPO binding in the prefrontal cortex (PFC), anterior cingulate cortex (ACC) and insula, relative to healthy

  • 0 views
  • 10 Jun, 2021
  • 1 location
ROOM-LIGHT: Effect of a Dynamic Lighting System in Depressed Inpatients

care arm with blinding of depression outcome, and data analyses. Randomisation will be 1:1. Inclusion criteria: a current episode of a major depressive episode as part of a unipolar or bipolar

drugs of abuse
depression
depressive episode
bipolar disorder
antidepressants
  • 10 views
  • 22 Jan, 2021
  • 1 location
8-week of PS128 RCT in Patients With Major Depressive Disorder

(DSM-V) criteria of major depressive episode in recent 2 years; Psychotropics including antidepressants, antipsychotics and hypnotics have been kept unchanged for at least 1 months. The exclusion

depression
psychiatric disorder
depressive episode
bipolar disorder
schizophrenia
  • 2 views
  • 24 Jan, 2021
  • 1 location
ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD)

The goal of the study is to conduct a comparative randomized trial of electroconvulsive therapy (ECT) vs. ketamine for patients with treatment resistant depression (TRD) in a real world setting with patient reported outcomes as primary and secondary outcome measures.

depression
ketamine
antidepressant therapy
depressive episode
treatment resistant depression
  • 1784 views
  • 29 Aug, 2021
  • 5 locations
PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)

Purpose: To determine whether COX-1 and COX-2 are detectable in the brains of individuals with MDD experiencing a major depressive episode (MDE). Endpoints

anxiety
depressive episode
scid
depressed mood
fluoxetine
  • 0 views
  • 22 Aug, 2021
  • 1 location
Infiltrations of OnaBotulinum Toxin A in Resistant Depression: Comparison of Two Facial Injection Sites.

The aim of the study is to evaluate in adult subjects with resistant depression the effect of an injection of botulinum toxin in the corrugator and procerus muscles, in comparison to the infiltration of the crow's feet area, in addition to the current antidepressant treatment.

antidepressants
depression
depressive episode
remission
  • 0 views
  • 23 Jan, 2021
  • 1 location
Desvenlafaxine Succinate (DVS) for Major Depressive Disorder (MDD) in Midlife Men and Women

The main objective of this study is to characterize a range of brain activation symptoms associated with depression and response to treatment in midlife men and women with MDD, using MRI and functional MRI. Moreover, in the female sub-group, the investigators will examine whether these brain activation symptoms are related …

desvenlafaxine
depression
functional magnetic resonance imaging
major depressive disorder
  • 74 views
  • 07 Nov, 2020
  • 1 location
Duloxetine for Major Depression in Peri-/Postmenopausal Women

The main objective of this study is to characterize a range of brain activation symptoms associated with major depression in peri- and post-menopausal women. Also, assessing brain activation before and after the treatment might help to uncover some mechanisms associated with the pathophysiology of depression and menopause.

major depressive disorder, single episode
depression
major depressive disorder
depressive episode
duloxetine
  • 49 views
  • 07 Nov, 2020
  • 1 location