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Found 69 clinical trials
Transcranial Direct Current Stimulation (tDCS) Cost-utility-analysis in Medical Care on Depressive Episode With One Drug Therapy Failure.

The purpose of this study is to determine the transcranial direct current stimulation (tDCS) cost-utility in the depression therapy. This is a 3 years medico-economics study with 1 year follow-up period involving patients with 1 or 2 depression treatment(s) failed. Eligible subject will be randomized in 2 groups, usual care …

depressive episode
psychotherapy
depressed mood
psychiatric disorder
antidepressants
  • 12 views
  • 29 Jan, 2021
  • 11 locations
Low Dose IL-2 Therapy in Patients With a Depressive Episode in the Course of a Bipolar Disorder

The purpose of this study will be to demonstrate improvement of the T regulatory cells (Treg) response, under add on low-dose Interleukin 2 (ld-IL2) in patients with bipolar disorders experiencing a depressive relapse

depressive episode
bipolar disorder
mood stabilizer
antidepressants
  • 7 views
  • 25 Jan, 2021
  • 1 location
Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode

This study aims at investigating if adjunctive buprenorphine at low dose to treatment as usual is effective in reducing severe suicidal ideas in major depressive episode, and at determining the

depressed mood
depression
analgesic
  • 0 views
  • 25 Jul, 2021
  • 11 locations
Social Stress and Suicide

Only vulnerable patients, when facing environmental stressors, attempt or commit suicide. Previous research demonstrated that suicide attempters usually misunderstand the social context and show impairments in decision making. Heart activity, endocrine and inflammatory response to stress were related with these features. For that, suicide attempters, in a context of social …

  • 0 views
  • 02 Feb, 2021
  • 1 location
Predict MDE Outcomes After MST

This trial attempts to explore the treatment outcome of magnetic seizure therapy (MST) for major depressive episode. Half of the participants will receive MST, while the other half will receive

  • 0 views
  • 26 Jan, 2021
  • 1 location
Comparing Uni- and Bi-lateral TBS in Major Depression

Repetitive transcranial magnetic stimulation (rTMS) is a Health Canada approved treatment for major depression. Theta burst stimulation (TBS) is a very promising new treatment for major depression that allows a 15-fold reduction in duration of daily sessions. However, no large scale naturalistic study has assessed the superiority of bilateral TBS …

  • 6 views
  • 25 Jan, 2021
  • 1 location
Brexpiprazole as Adjunctive Therapy in Adults With Major Depressive Disorder

The clinical trial will investigate the effect of brexpiprazole on the concept of life engagement in patients with MDD with a current depressive episode.

  • 0 views
  • 15 Apr, 2021
  • 1 location
  • 0 views
  • 24 Mar, 2021
  • 1 location
RCT for Electroconvulsive Treatment Followed by Cognitive Control Training

Major depressive disorder (MDD) is worldwide one of the most prevalent and disabling mental health conditions. Electroconvulsive therapy (ECT) is a safe and effective treatment even though 6-month relapse rates are high. Cognitive side effects of ECT, such as reduced cognitive control, might trigger mechanisms that increase relapse in patients. …

  • 0 views
  • 24 Jan, 2021
Efficacy of Edupression.Com in Depressive Patients

The aim of the study is to investigate the efficacy and adherence of the digital self-help programme edupression.com.

  • 0 views
  • 07 May, 2021
  • 1 location