Found 62 clinical trials
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Accepting adults
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For all genders
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Currently Recruiting
Major Depressive Disorder (MDD) Study
the MDD Study if: You are 18-65 years old You have been diagnosed with recurrent Major Depressive Disorder (MDD) You are currently experiencing a major depressive
- 126 views
- 23 Nov, 2020
- 1 location
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Accepting pediatric ages
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Accepting adults
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For all genders
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Currently Recruiting
Outpatient study for an investigational medication for depression
Outpatient study for an investigational medication for depression
- 1092 views
- 08 Nov, 2020
- 1 location
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Phase 3 trial
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Accepting adults
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For all genders
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Currently Recruiting
Researching the effectiveness of cariprazine for treatment of depressive episodes in patients with bipolar disorder.
Researching the effectiveness of cariprazine for treatment of depressive episodes in patients with bipolar disorder.
- 260 views
- 23 Nov, 2020
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Neurophysiological Markers in the Depressive Episode Characterized by Anhedonic Drug Resistance: Evaluation of Motor Skills and P300 Wave
Depression is currently the leading cause of disability and suicide death worldwide. Several studies, however, have shown that a significant proportion of patients do not respond to standard antidepressants, especially since their symptomatology is dominated by anhedonia or psychomotor retardation reflecting central dopaminergic dysfunction. In order to improve the efficiency …
- 0 views
- 27 Jan, 2021
- 2 locations
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Minocycline as Adjunctive Treatment for Treatment Resistant Depression
treatment approach. This study is a 12 week, double-blind, placebo-controlled trial of minocycline as add-on treatment for patients suffering from a major depressive episode who have failed to
- 0 views
- 24 Jan, 2021
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor in Participants With Treatment Resistant Major Depressive Disorder
current moderate to severe depressive episode.
- 0 views
- 11 Apr, 2021
- 213 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Genetic Disease
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Currently Recruiting
Optimal Electrical Stimulus During Electroconvulsive Therapy
, 400 patients in each arm. Inclusion criteria: At least 18 years of age at the time of inclusion Diagnostic criteria fulfilled for unipolar, or bipolar depressive episode according to
- 98 views
- 25 Jan, 2021
- 2 locations
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Multi-country trial
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Phase 4 trial
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Psychiatry/Psychology
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Currently Recruiting
Vortioxetine in Patients With Depression Coexisting With General Anxiety Disorder (GAD)
This study evaluates the effectiveness of vortioxetine on depressive symptoms in patients with depression coexisting with generalized anxiety disorder.
- 75 views
- 19 Mar, 2021
- 27 locations
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Psychiatry/Psychology
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Currently Recruiting
Cerebral Neuroinflammation During Major Depressive Episode
the investigators make the following assumptions: 1) neuroinflammation in MDD can be measured by the [18 F ] DPA- 714 ; 2) it is accompanied by anatomical and functional changes in the frontal subcortical loops, strongly involved in MDD ; 3) neuroinflammation in patients might be a biomarker related to …
- 7 views
- 25 Jan, 2021
- 2 locations