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Found 2129 clinical trials
Featured trial
The Neureka Project

The Neureka Project aims to develop new ways of detecting disorders of the brain early. From mental health conditions to dementia, we want to find out who is at risk and why, so we can develop preventative interventions that can be used the world over. To do this, we are taking …

Online studies
  • 6387 views
  • 28 Sep, 2022
  • 1 location
  • Online study
Featured trial
Pain Sensitivity and Unpleasantness in People with Alzheimer’s Disease and/or Cancer

The University of Tennessee Health Science Center in Memphis, TN has a research opportunity for people to participate in the study: Pain Sensitivity and Unpleasantness in People with Alzheimer’s Disease and Cancer. Specifically, they are looking for individuals over the age of 60 for 1 of 3 groups: (1) those …

primary cancer
AIDS
cancer
Online studies
  • 41 views
  • 28 Sep, 2022
  • 1 location
  • Online study
Featured trial
Preventing Alzheimer's With Cognitive Training (PACT)

Dementia is the most expensive medical condition in the US and increases in prevalence with age. More than 5 million Americans have Alzheimer's disease, the most common form of dementia. Mild cognitive impairment is a transitional stage between normal cognitive aging and Alzheimer's disease or another type of dementia, and …

cognitive impairment
cognitive stimulation
dementia
mild cognitive impairment
Accepts healthy volunteers
  • 1 views
  • 28 Oct, 2022
  • 5 locations
Featured trial
Cognitive Fitness for Depression in Older Adults

This research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with

  • 85 views
  • 22 Jan, 2022
  • 1 location
Featured trial
Ketamine for the Treatment of Depression in Parkinson's Disease (KET-PD)

The main purpose of this study is to examine the efficacy and safety of a repeated dosing ketamine infusion paradigm compared to placebo in individuals with PD. A subset of participants in each arm will undergo baseline and post-treatment PET and fMRI scans, to examine whether changes in synaptic density …

hoehn and yahr scale
depressive disorder
depressed mood
ketamine
depression
  • 43 views
  • 07 Oct, 2022
  • 1 location
Featured trial
Methodology Issues in a Tailored Light Treatment for Persons With Dementia

Tailored light treatment will increase sleep efficiency, reduce depression and reduce agitation scores in those with Alzheimer's disease and related dementia

mini-mental state examination
agitation
depressed mood
mental state examination
alzheimer's disease
  • 6 views
  • 01 Apr, 2022
  • 2 locations
Featured trial
A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (LIGHTHOUSE)

score means more severe PD symptoms. Part I assesses non-motor experiences of daily living, including but not limited to memory loss, problems sleeping, pain, depression, and anxiety.

movement disorder
hoehn and yahr scale
motor symptoms
depression
  • 1 views
  • 16 Nov, 2022
  • 2 locations
Featured trial
Dementia Family Caregiver Study

The proposed study will test a 3-month, community health worker (CHW) delivered home visit, culturally and language-appropriate intervention for ethnic and underserved dementia family caregivers of persons with dementia (PWD) using wearable technology for real time monitoring of caregivers' stress and sleep. The CHW delivered home visit intervention includes stress …

alzheimer's disease
Accepts healthy volunteers
  • 27 views
  • 30 Apr, 2022
  • 1 location
Featured trial
Depression Research Study

The Shoreline study is evaluating an investigational oral medication to see if it reduces symptoms of moderate-to-severe depression.  

severe depression
depressed mood
  • 862 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS).

A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS).  

major depressive disorder
major depressive episode
depressed
depression
  • 78 views
  • 22 Dec, 2020
  • 1 location