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Found 2761 clinical trials
Cardio-pulmonary Rehabilitation and Sleep Quality

In this prospective cohort study the investigators aim to evaluate the effect of pulmonary rehabilitation on sleep quality. Disturbed sleep is associated with, frequent exacerbations, increase in the severity of disease and increased mortality in chronic obstructive pulmonary disease (COPD). Sleep quality is a good predictor of quality of life …

heart failure
pulmonary rehabilitation
rehabilitation program
  • 19 Apr, 2022
  • 1 location
Defecation Function and Quality of Life in the Patients Treated With Surgery for Slow Transit Constipation

Although surgical options for slow transit constipation (STC) have been proven to be a definite treatment, improvements in the associated defecation function and quality of life are rarely studied. This study aims to investigate the effectiveness of total or subtotal colectomy, with respect to short- and long-term defecation function and …

  • 14 May, 2022
  • 1 location
The Effect of Cigarette Smoke on Sleep Quality and Physical Activity in People With Multiple Sclerosis (Smoke-MS)

Current evidence suggests that cigarette smoke increases disease progression in people with multiple sclerosis (PwMS) and worsen their symptoms. 70% of PwMS report sleep disturbances that negatively affects their quality of life. Cigarette smoke has been found to be associated with sleep disturbances in healthy adult smokers, but this relationship …

  • 21 Apr, 2022
  • 1 location
BIOmarkers of MIGraine: a Proof of Concept Study Based on the Stratification of Responders to CGRP Monoclonal Antibodies

Migraine is the 2nd most disabling neurological disease. It affects 14.7% of the population (children and adults) of whom 80% are female. In the European Union, the total annual cost of migraine is of 111 billion euros. If not adequately treated, migraine can evolve into the more severe chronic form …

  • 05 May, 2021
  • 3 locations
Study for the Evaluation of the Feasibility of Applying Advanced MRI Scanning in Pediatric Clinical Practice

The purpose of this research study is to evaluate the feasibility in conducting advanced MRI sequences in a pediatric clinical setting. The study will be observational in nature, and will only evaluate the studies of pediatric patients who have already been prescribed an advanced MRI for clinical neurological purposes. The …

5 minute
  • 23 Feb, 2022
  • 1 location
Measuring the Impact of Taking Care in the Context of an Innovative System for Keeping Dependent Elderly People in Their Homes (DIAPASON)

The purpose of this study is to compare life quality of patients taking care by DIAPASON 92 with patients or residents from control group EHPAD (retirement home)

  • 09 Feb, 2022
  • 1 location
AIM's Writing for Healing: A Workshop for Individuals Living With Paralysis

The UAB Institute for Arts In Medicine (AIM) is currently implementing an expressive emotional writing pilot project for adults with paralysis caused by neurological conditions such as traumatic head or spinal cord injury.

multiple sclerosis
Accepts healthy volunteers
spinal cord
degenerative disc disease
  • 24 Mar, 2022
  • 1 location
Validation of the Pain Relief Measure

The purpose of this study is to provide evidence for the empirical and clinical utility of a novel pain relief measure, the IPR, dimensions of which will be validated against the present gold standards for pain measurement.

pain relief
  • 12 Apr, 2022
  • 1 location
LOng COvid COmorbidities: Endocrine,Metabolic,Neuropsychiatric,Muscle,Cardiovascular,Pulmonary,Dermatologic Dysfunctions (LO-COCO)

Considering the compelling amount of studies focused on patients in the active phase of COVID-19 disease and the scarcity of studies focused on patient cured from disease aimed at evaluating the sequelae of SARS-CoV-2 infection, the purpose of the study is to investigate whether in patients recovered from COVID-19 disease, …

  • 24 Apr, 2022
  • 1 location
Precision Opioid Care After Cesarean Delivery (PRECISE-CD) (PRECISE-CD)

The purpose of this research is to study serious clinical problems from both surgical pain and oxycodone and opioid use in women having a Cesarean Delivery to improve the safety and efficacy of surgical pain relief. This research will ultimately improve the safety and efficacy of surgical pain relief with …

  • 28 Apr, 2022
  • 1 location